Page 590 - Veterinary Immunology, 10th Edition

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FIG. 19.8 The three major receptor types found on mouse NK
cells. Ly49 recognizes MHC class I molecules and suppresses NK
cytotoxicity. NKG2D is a receptor for molecules such as MIC-A and
MIC-B. These molecules are commonly expressed on stressed,
virus-infected, or tumor cells. CD16 binds immunoglobulins and
triggers target cell death by antibody-dependent cellular cytotoxicity.
Remember that in other mammals, Ly49 may be replaced by KIR
receptors.

FIG. 19.9 Some of the receptors expressed on NK cells.

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