Page 86 - Poultry-Punch April 2020 edition
P. 86

POULTRY PUNCH                                                                          ARTICLE


                                             one of the most farmed animal species  Moreover, phages also do not dissociate
             Bacteriophages are              in  the  world  which  makes  it  a  leading  from  bacterial  targets  once  irreversibly
                                             contributor  to  the  poultry  industry.  adsorbed.
            natural micro-organisms          Nonetheless,  use  of  antimicrobials  in   Phage  Therapy  is  now  emerging  as
            made up of only genetic          chicken  plus  other  animal  production  a  useful  tool  in  controlling  bacterial
                                             will accelerate the development of AR in  infections  and  at  the  same  time  is
            material namely DNA              pathogens which poses danger to human  encouraging  the  growth  of  healthy
            and RNA plus protein.            beings.                          poultry.  With  the  use  of  Artificial
                                               This  is  because  when  an  antibiotic  Intelligence,  it  can  be  determined
            Moreover, they also              is  used  in  improper  way,  it  may  leave  whether  the  phages  are  lytic  or  not
            do not damage the                behind  some  bacterial  strains  that  as only lytic phages are used in animal
                                             resist  the  drug  which  can  multiply  and  health. This is because lysogenic phages
            beneficial microbiome            become  the  dominating  population.  are  dormant  and  embed  themselves  in
            balance. These naturally         This   dominating   population   can  the bacterial cell wall to live off it without
            occurring organisms              also  be  transferred  to  others.  These  destroying  it.  On  the  other  hand,  lytic
                                             resistant  bacteria  can  transfer  from  phages cause lysis which is destruction
            only eliminate selected          poultry products to humans when they  of bacteria.

            bacteria. More and               consume meat contaminated with these   The Need for Quality Feed
                                             pathogens.  This  has  prompted  many
            more companies                   countries  to  withdraw  antibiotics  from   When  it  comes  to  chicken  it  takes
            are embracing                    being used in animal production and set   less than three hours for the feed to be
                                                                              digested  and  absorbed.  To  compensate
                                             up  regulatory  authorities  for  selected
            bacteriophages instead           antibiotics as well encourage the use of   for  the  relatively  short  digestive  tract
            of antibiotics when              bacteriophages.  This  has  also  led  to  a   and  rapid  digestion  transit  time,  high-
                                                                              performing  birds  need  easily  digestible
            it comes to poultry              surge in demand for healthier and safer   nutrient-dense  feed  where  nutrients
                                             alternatives  to  antibiotics  for  disease
            production.This is largely       prevention and control.          are critical. The rates of genetic change
                                                                              in  growth  and  feed  efficiency  over  the
            because bacteriophages           Bacteriophages as a Better       years have also changed the physiology

            are safe as they are only        Alternative                      of the birds. Nutrient requirements and
                                               Bacteriophages  have  emerged  as  a  nutritional management have therefore
            able to infect bacterial         viable  alternative  to  reduce  antibiotic  changed  to  harvest  maximum  of  the
            cells not human or               usage in poultry rearing.  Bacteriophages  genetic  potential  of  the  new  strains.
            animal cells. Without            are natural micro-organisms made up of  The  high  genetic  potential  of  current
                                             only  genetic  material  namely  DNA  and  poultry  strains  can  only  be  achieved
            the presence of their            RNA  plus  protein.    Moreover,  they  also  with properly formulated feeds that are
            bacterial host they              do not damage the beneficial microbiome  protein and energy-dense.
                                                                                Moreover,  the  feed  additives  to
                                             balance.  These  naturally  occurring
            become inactive within           organisms  only  eliminate  selected  use  for  destruction  and  prevention  of
            48 hours. In comparison          bacteria.  More  and  more  companies  bacterial infection in farmed animals as
                                             are  embracing  bacteriophages  instead  well as transmission to humans must be
            to antibiotics a single          of  antibiotics  when  it  comes  to  poultry  regulatory  approved  as  well  as  should
            phage can destroy a              production.  This  is  largely  because  eliminate  pathogens.  It  should  also  be
            multiple bacterium by            bacteriophages are safe as they are only  non-toxic with no side effects on poultry
                                             able  to  infect  bacterial  cells  not  human  and must be easy to apply and use. Other
            multiplying in bacteria          or  animal  cells.  Without  the  presence  things  which  poultry  farm  owners  and

            itself which is why fewer        of  their  bacterial  host  they  become  managers  must  keep  in  mind  are  the
                                             inactive  within  48  hours.  In  comparison  composition and quality of feed, nutrient
            doses are required per           to antibiotics a single phage can destroy  value,  digestibility,  moisture  retention,
            administration.                  a  multiple  bacterium  by  multiplying  palatability  as  well  as  any  possible
                                             in  bacteria  itself  which  is  why  fewer  hazards that long term consumption may
                                             doses  are  required  per  administration.  cause.



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