Page 127 - The Manga Guide to Biochemistry
P. 127
liver small There are four main steps
intestine to the process that turns
ingested lipids into fat.
Let's take a look!
VLDL and VLDL chylomicron
Chylomicron
triacylglycerol
Fat Cell
lipoprotein lipase Blood
vessel
fatty acid glycerol
endothelial
cell
fatty acid glycerol
Energy Recombined and stored
source in triacylglycerol
Triacylglycerol is transported in the blood by very low- Break it
density lipoprotein (VLDL) that was created in the liver and down!
by chylomicron that was absorbed and created in the small
intestine. enzyme
Endothelial cells, which line blood vessels, have an enzyme called
lipoprotein lipase on their surfaces. When triacylglycerol is trans-
ported through the capillaries in adipose tissue, muscles, and
other tissues, it encounters lipoprotein lipase and is hydrolyzed
into fatty acids and glycerol.
Those fatty acids and glycerol are captured in adipose tissue.
The captured fatty acids and glycerol are recombined and stored
in triacylglycerol.
Ooh And when this happens,
fat steadily increases!