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42. MÉCANISMES DE LA CHIMIORÉSISTANCE 811

http://www.infobiogen.fr/services/chromcancer/genes/LRPID120.html
GSH/GST
DOLPHIN D. et al., Glutathione : Chemical, Biochemical and Medical Aspects, Part A,
Wiley-lnterscience Publications eds, N.Y., 1989.
SCHRÔDER C.P. et al., Cancer Invest., 1996, 14, 158-168.
SCHULTZ M. et al., Adv. Drug Delivery Rev., 1997, 26, 91-104.
SIES H., Free Rad. Bio/. Med., 1999, 27, 916-921.
SALINAS A.E., WONG M.G., Curr. Med. Chem., 1999, 6, 279-309.
ALTÉRATION DES CIBLES

TOPO-ISOMÉRASES I ET II
URASAKI Y. et al., Characterization of a novel topoisomerase I mutation from a camp-
tothecin-resistant human prostate cancer cell line, Cancer Research, 2001, 61, 1964-
1969.
CHANG J.Y. et al., Novel mutation of topoisomerase I in rendering cells resistant to
camptothecin. Cancer Research, 2002, 62, 3716-3721.

B-TUBULINE
BURKHART C.A. et al., The role of B-tubulin isotypes in resistance to antimitotic drugs,
Biochimica et Biophysica Acta, 2001, 1471, 01-09.
HE L. et al., Mutations in B-tubulin map to demains involved in regulation of microtubule
stability in epothilone-resistant cell lines, Molecular Cancer Therapeutics, 2001, 1,
3-10.
RÉPARATION DE L'ADN
NICKOLOFF J.A., HOEKSTRA M.F., DNA damage and repair, vol. 2 : DNA Repair in
Higher Eukaryotes, Humana Press Inc. Eds, Totowa N.J.,
KARP G., Biologie cellulaire et moléculaire, De Boeck Université éd., Bruxelles, 1998,
588-596.
COOPER G.M., La Cellule, De Boeck Université éd., Bruxelles, 1999, 190-221.
WOOD R.D., Human DNA repair genes, Science, 2001, 291, 1284-1289.
BERNSTEIN C. et al., DNA repair/pro-apoptotic dual-role proteins in five major DNA
repair pathways : fail-sale protection against carcinogenesis, Mutation Research,
2002, 145-178

OGAT
TENTORI L. et al., Inhibition of O°-alkylguanine-DNA alkyltransferase or poly(ADP-
ribose)polymerase increases susceptibility of leukemic cells to apoptosis induced by
temozolomide, MolecularPharmacol., 1997, 52, 249-258.
MIDDLETON M.R. et al., O-methylguanine-DNA methyltransferase in pre-treatment
tumor biopsies as a predictor of repense to temozolomide in melanoma, British
J. Cancer, 1998, 78, 1199-1202.