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Medicinal plants (PG 101)                                        Level 1                              Clinical Pharmacy-PharmD



                               4- ELECTRON TRANSPORT CHAIN AND OXIDATIVE

                                                    PHOSPHORYLATION

                    Like  a series of  power  converters, the  electron transport  chain  takes  the  energy

                      placed in NADH and FADH2 and uses it to charge ADP into ATP. This happens

                      in a series of nine steps in the inner membrane of the mitochondria.

                    The first charged molecule to enter the electron transport chain is NADH. NADH

                      charges a flavoprotein at the beginning of the electron transport chain. This

                      flavoprotein then sends its energy down a set of enzymatic steps, releasing a little


                      energy during each step until cytochrome a3 takes the last bit of energy to produce
                      O2. I bet you did not know that you made O2. Unfortunately, this O2 is quickly


                      hydrolyze, picking up H2 to form H2O.













































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