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Clinical pharmacy PharmD program                     Third level                          Phytochemistry-1 (PG-504)














                                                    Phytic acid



              •  The hexaphosphoric ester of inositol.

                                                          2+
                                                   2+
              •  Forms insoluble salts with Ca , Mg , Fe & Cu , Prevent their absorption
                                                                         2+
                                                                 2+
                 from diet in the small intestine.
              •  So it is better to avoid maize and legumes in diet of anaemic patient with

                 iron rich diet or haematinic drugs.

                                                 2) Acidic sugars:

                     There are three important types of acidic sugars: (see above)


                a) Aldonic acids: (see above)

              ▪  They are obtained by oxidation of the carbonyl group.

                                   Ascorbic acid “Vitamin C”: (Enol form).



                             CH 2 -OH

                        HO-CH        O
                                                O



                               OH         OH


              Preparation:


               1)  It could be extracted from citrus fruits, sore hips, blackcurrants.

               2)  Chemical synthesis from glucose.

               3)  Vitamin C (L-ascorbic acid) is an important aldonic acid lactone.










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