Page 282 - Pharmacognosy 2 PG303

Pharmacognosy-2 (PG303) Level 2 Clinical Pharmacy-Pharm D

3) with fehling solution give (2) Powder/ether, extract
red ppt. with CHCl₃, dry on filter
paper, yellow stain, by
treatment with hot saturated
boric acid solution, an
orange red color is
produced turns into bluish
black color by addition of
ammonia.

Uses ▪ treatment of cough ▪ anti-emetic ▪ appetite stimulant and ▪ Stimulant and
(expectorant) ▪ Aromatic flavoring and digestive. carminative properties .
.
▪ sweetening agent condiment ▪ rice colorant. ▪ Prevent vomiting ( for
▪ demulcent ▪ Anti-inflammatory ➢ Curcumin is proved to sea sickness)
▪ anti-inflammatory (arthritis ,bronchitis) have : ▪ Antifungal against
.
▪ anti-ulcer ▪ Circulatory stimulant, it is ▪ antioxidant Candida albicans
▪ antioxidant & antitumor a ▪ anti-inflammatory )
▪ antiviral good choice for chronic treat arthritis)
▪ for menopausal disorder cold hands and feet. ▪ anticholesterolemic
➢ Side effects : ▪ lower cholesterol and (prevent heart
Electrolyte disturbance prevent the blood from diseases)
(hypokalemia, hypertension) clotting (prolongation of ▪ anticancer
due to the corticosteroid -like bleeding time) ▪ treat HIV .
action of glycyrrhizin
Notes ▪ Interaction with drugs: ➢ Adulteration & detection? ➢ Curcuma is prepared
✓ With diuretics cause ✓ Precautions: by (steam distillation)
hypokalemia and paralysis. ✓ should not be used by ➢ The bioavailability of
✓ Increase the adverse effect of children under 2 years curcumin increased
corticosteroids. of age . when co-administrated
✓ Toxicity of digoxin increased ✓ excessive doses may with black pepper.
+
when K level is low. cause mild heartburn.
✓ It should not be used
during pregnancy!!?

234