Page 286 - Pharmacognosy 2 PG303
P. 286

Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

    Jalap Root    Rauwolfia Root   Krameria Root   Veratrum    American
 (Radix Jalapae)   (Indian Snake Root  ,  (Radix Ratanhiae  ,  Rhizome   Veratrum
   ةبلجلاا ةنرد   Sarpaganda)   Peruvian Rhatany)   )White Hellebore  ,  (Green Hellebore)
 يدنهلا نابعثلا رذج                   Rhizoma veratri           رضخلاا قيرخلا
                                           Albi)
                                         ضيبلاا قيرخلا
 Origin    Dried tuberous roots of    Dried roots and rhizomes   Dried roots of Krameria    Dried rhizomes of    Dried rhizomes of
 Ipomea purga,    of Rauwolfia serpentina   triandra family     Veratrum album   Veratrum viride  ,


 family Convolvulaceae   family Apocyanaceae   Krameriaceae   L ,.family   family Liliaceae
 ▪  Known as Mexican                Liliaceae            ▪  It resembles the
 Jalap (Vera Cruz) .                                       white species but
                                                           usually cut
                                                           longitudinally
                                                           (white veratrum is
                                                           commonly entire)  .
                                                           It is brighter
                                                           yellowish brown in
                                                           color.





 Active   ▪  8-12% Glycosidal resin  ✓  Alkaloids)1.2-1.4%)    ▪  About 15% condensed   ▪  Alkaloids (1-  ➢  Alkaloids which
 constituents    (convolvulin ,jalapin)   ➢  the most important are :   (catechol) tannins   2%)   can be  classified
 ▪  Coloring matter.   •  reserpine   ▪  Lipophilic   (Protoveratrines    into three groups:
 ▪  Mannitol.   •  rescinnamine   benzofuran   and Jervine)     ▪  Alkamines
    •  serpentine   derivatives .   ✓  The roots are        (steroidal bases)  ,
 ✓  Resin (has a CNS   ▪  Sugars.      said to be richer    e.g ,.germine and
 depressant effect) .                  in alkaloids         veratramine .
                                       than the          ▪  Esters of
                                       rhizome and          alkamines with
                                       must not be          organic acids ,
                                       discarded .          e.g ,.cevadine and
                                                            germidine.

     236
   281   282   283   284   285   286   287   288   289   290   291