Page 285 - Pharmacognosy 2 PG303
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Pharmacognosy-2 (PG303) Level 2 Clinical Pharmacy-Pharm D
Jalap Root Rauwolfia Root Krameria Root Veratrum American
(Radix Jalapae) (Indian Snake Root , (Radix Ratanhiae , Rhizome Veratrum
ةبلجلاا ةنرد Sarpaganda) Peruvian Rhatany) )White Hellebore , (Green Hellebore)
يدنهلا نابعثلا رذج Rhizoma veratri رضخلاا قيرخلا
Albi)
ضيبلاا قيرخلا
Origin Dried tuberous roots of Dried roots and rhizomes Dried roots of Krameria Dried rhizomes of Dried rhizomes of
Ipomea purga, of Rauwolfia serpentina triandra family Veratrum album Veratrum viride ,
family Convolvulaceae family Apocyanaceae Krameriaceae L ,.family family Liliaceae
▪ Known as Mexican Liliaceae ▪ It resembles the
Jalap (Vera Cruz) . white species but
usually cut
longitudinally
(white veratrum is
commonly entire) .
It is brighter
yellowish brown in
color.
Active ▪ 8-12% Glycosidal resin ✓ Alkaloids)1.2-1.4%) ▪ About 15% condensed ▪ Alkaloids (1- ➢ Alkaloids which
constituents (convolvulin ,jalapin) ➢ the most important are : (catechol) tannins 2%) can be classified
▪ Coloring matter. • reserpine ▪ Lipophilic (Protoveratrines into three groups:
▪ Mannitol. • rescinnamine benzofuran and Jervine) ▪ Alkamines
• serpentine derivatives . ✓ The roots are (steroidal bases) ,
✓ Resin (has a CNS ▪ Sugars. said to be richer e.g ,.germine and
depressant effect) . in alkaloids veratramine .
than the ▪ Esters of
rhizome and alkamines with
must not be organic acids ,
discarded . e.g ,.cevadine and
germidine.
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