Page 285 - Pharmacognosy 2 PG303
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Pharmacognosy-2 (PG303)                              Level 2                Clinical Pharmacy-Pharm D

                                        Jalap Root                Rauwolfia Root               Krameria Root               Veratrum              American
                                        (Radix Jalapae)            (Indian Snake Root  ,        (Radix Ratanhiae  ,         Rhizome              Veratrum
                                              ةبلجلاا ةنرد             Sarpaganda)              Peruvian Rhatany)        )White Hellebore  ,   (Green Hellebore)
                                                                      يدنهلا نابعثلا رذج                                  Rhizoma veratri           رضخلاا قيرخلا
                                                                                                                                Albi)
                                                                                                                             ضيبلاا قيرخلا
                  Origin          Dried tuberous roots of       Dried roots and rhizomes     Dried roots of Krameria    Dried rhizomes of     Dried rhizomes of
                                  Ipomea purga,                 of Rauwolfia serpentina      triandra family            Veratrum album        Veratrum viride  ,


                                  family Convolvulaceae         family Apocyanaceae          Krameriaceae               L ,.family            family Liliaceae
                                  ▪  Known as Mexican                                                                   Liliaceae            ▪  It resembles the
                                    Jalap (Vera Cruz) .                                                                                        white species but
                                                                                                                                               usually cut
                                                                                                                                               longitudinally
                                                                                                                                               (white veratrum is
                                                                                                                                               commonly entire)  .
                                                                                                                                               It is brighter
                                                                                                                                               yellowish brown in
                                                                                                                                               color.





                  Active          ▪  8-12% Glycosidal resin  ✓  Alkaloids)1.2-1.4%)         ▪  About 15% condensed      ▪  Alkaloids (1-     ➢  Alkaloids which
                  constituents        (convolvulin ,jalapin)    ➢  the most important are :   (catechol) tannins            2%)                  can be  classified
                                  ▪  Coloring matter.               •  reserpine            ▪  Lipophilic                   (Protoveratrines     into three groups:
                                  ▪  Mannitol.                      •  rescinnamine             benzofuran                  and Jervine)     ▪  Alkamines
                                                                    •  serpentine               derivatives .           ✓  The roots are         (steroidal bases)  ,
                                                                ✓  Resin (has a CNS         ▪  Sugars.                      said to be richer    e.g ,.germine and
                                                                   depressant effect) .                                     in alkaloids         veratramine .
                                                                                                                            than the         ▪  Esters of
                                                                                                                            rhizome and          alkamines with
                                                                                                                            must not be          organic acids ,
                                                                                                                            discarded .          e.g ,.cevadine and
                                                                                                                                                 germidine.

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