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Protozoal Microorganisms as Intestinal Parasites   65


                                                                    be caused by pathogenic bacteria, viruses, or parasites.
                       MICROSCOPIC DIAGNOSTIC                       Because treatment for the various types of dysentery is

                                   FEATURE                          quite different, it is necessary to determine the cause of
                                                                    the dysentery prior to initiating treatment. Diagnosis is
                                                                    most often made through clinical signs and stated symp-
                    General                                         toms expressed by the patient, but dysentery should be
                    Classification       Amoeba
                                                                    confirmed by microscopic examination because  diarrhea
                    Organism             Iodamoeba butschlii        by any of the three entities listed previously are  capable of
                    Specimen Required  Stool specimen               producing similar signs and symptoms.  Bacterial dysen-
                                                                    tery is diagnosed and the causative organism  determined
                    Stage                Trophozoites most
                                         diagnostic stage           by culture of the bacterial strain on nutrient media, after
                                                                    which an antibiotic sensitivity test will indicate the anti-
                    Size                   6–20 μm for tropho-
                                         zoite and 6–15 μm for      bacterial agent that should be most effective in control-
                                         cyst stages                ling the disease. Viruses may be grown in cell cultures but
                    Shape                Irregularly shaped         this procedure is quite time consuming, and may become
                                         and elongated tro-         contaminated. The most common manner of  diagnosing
                                         phozoites and slightly     a viral infection is by the indirect process of the antibody
                                         oval cysts                 titer where the body’s immune system  reacts to the infec-
                    Motility             Nondirectional             tion and by the presence of clinical signs and symptoms.
                    Nucleus(i)           1 for trophozoites         Parasites, on the other hand, are discovered by examina-
                                         and 1 for cysts            tion of blood and body wastes by microscopic evalua-
                    Cytoplasm            Sometimes includes         tion of wet mounts and stained specimens that may also
                                         ingested bacteria and        necessitate concentration techniques.
                                         is vacuolated
                    Other Features         Large and concentric
                                         karyosomes in both         OTHER ASSOCIATED CONDITIONS
                                         stages                     OF INTESTINAL INFECTIONS
                                         Large defined glyco-
                                         gen vacuole is charac-     Balantidium coli, a normal parasite of swine as described
                                         teristic of this species   previously, is a pathogenic ciliate and can cause severe
                                                                    colitis, or irritation of the bowel, and is mentioned for the
                   I. butschlii
                                                                    following reasons. The clinical manifestations are very
                              Trophozoite               Cyst
                                                                    similar to the intestinal amoebal infections where the diag-
                                                                    nosis is most often made by the microscopic examination
                                                                    of stool specimens before treatment is begun. Treatment
                                                                 Delmar/Cengage Learning  used primarily for bacterial infections. Pseudomembra-
                                                                    for B. coli infections is with tetracycline, an antibiotic
                                                                    nous colitis may mimic parasitic infections, but is an
                                                                     infection of the colon that is often caused by a bacterium
                                                                    called Clostridium difficile. The illness is characterized
                                                                    by offensive-smelling diarrhea, fever, and abdominal pain,
                                                                    which are similar to signs and symptoms presented by
                                                                    victims of an intestinal parasitic disease. Therefore, para-
                   DIFFERENTIATING BACTERIAL                        sitic or bacterial infections should be ruled out by specific
                   DYSENTERY FROM AMEBIC                            lab tests to provide appropriate treatment.
                   DYSENTERY                                            Other intestinal diseases characterized by  severe
                                                                    dysentery are Crohn’s disease and ulcerative coli-
                   Dysentery is a disease that is characterized by diarrhea   tis, but both of these conditions are rare in the tropics
                   and contains both blood and mucus. The condition may   where parasitosis abounds. Radiological studies and
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