Page 49 - Practical Technology 2025

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Clinical Pharmacy-Pharm D Level Three 2 Semester 2024/2025 Pharmaceutical Technology (PT 607)

Lab (5): (Weight Uniformity Test)

Weight Variation:

In manufacturing tablets our aim is to produce tablet that can be validated as to its safety,
efficacy, and reliability; so, each tablet is designed to have certain weight and to check the

uniformity of weight.

1- 20 tablets previously selected at random were weighed. Then the average weight was

determined.
2- Tablets were weighed individually and the percentage deviation of its weight from the

average weight was determined for each tablet.

3- The deviation of individual weight from the average weight should not exceed the
pharmacopeial limits.

The tablets meet the pharmacopeial limits weight variation test if:

No more than two tablets of 20 tablets are outside the percentage

limit and no tablet differs by more than twice the percentage limit.

According to USP (most commonly used):

According to BP:

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