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Бог малын сохор догол өвчнөөс сэргийлэх идэвхгүйжүүлсэн вакцины загвар 2013
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VII. ХУРААНГУЙ

ABSTRACT
RESULTS OF THE STUDY ON PREPARATION AND EVALUTION OF A PHENOL

INACTIVATED VACCINE CANDIDATE AGAINST CONTAGIOUS AGALACTIA
Ts. BATBOLD

Contagious agalactia is an infectious disease of sheep and goats, which has

been known since 1800. Main causative agent of this infection is M. agalactiae.
Contagious agalactia broadly spread out in Europe, Asia, North America. It mainly

occurs in countries where mostly breeding small ruminants, particularly in France,

Holland, Austria, Hungary, Greece, Syria, Iran, Mongolia and other countries.
Contagious agalactia of small ruminants are endemic infection in Mongolia and it has

been registered in the Westren and Central regions of country, which is causing a
huge loss to the economy. The official disease reports of the Governmental

Implementation Agence-Department of Veterinary and Animal Breeding of Mongolia
during the last 10 years had been registered this infection in 12 Aimags and in this

area had infected more than 28.217.0 animals .

Vaccines for the prevention of contagious agalactia due to M. agalactiae
infection have been used in countries, where this infection is an endemic. Now days in

veterinary practice are using 2 kind vaccines: inactivated and live culture vaccines. No
single vaccine has been universally adopted, and no standard methods of preparation

and evaluation would be apply to all vaccines that have been used. In several
countries are using live culture vaccines, but it is can be source of infection and

inhibited to use it in most countries. I those countries where live culture vaccines for

prevention of this infection are not acceptable, research has been focused on the use
and development of inactivated vaccines. In many countries researchers have been

found that, vaccines inactivated with phenol or saponin gave a good protection,

compare with formalin or heat inactivated vaccines. But in Mongolia, for the
immunization of small ruminants against contagious agalactia is using formalin

inactivated or live culture vaccines.

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