Page 156 - phytochemistry I - PharmD Clinical

Bufadienolides: C24 (24 carbon atoms) are cardiac glycosides with an
aglycone having a six-membered lactone ring in the C17 position of the
steroid nucleus. Bufadienolides are found in squill cardiac glycosides.

Cardiac glycosides containing 3 or 4 monosaccharides are soluble in
water. Aglycones of cardiac glycosides are soluble in organic solvents
and practically insoluble in water. Cardiac glycosides easily hydrolyze and
yield the sugars and aglycone.

1. Digitalis lanata family

Dried leaves of Digitalis purpurea, Digitalis
Scrophulariaceae dried at a temperature below 60ºC.

Source Primary Secondary Aglycone
Digitalis glycoside glycoside digitoxigenin
purpurea Purpurea digitoxin
glycoside A
Digitalis lanata Purpurea gitoxin gitoxigenin
glycoside B
Lanatoside A digitoxin digitoxigenin
Lanatoside B gitoxin gitoxigenin
Lanatoside C Digoxin digoxigenin

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