Page 116 - International guidelines for groin hernia management
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Hernia

           Incidence and epidemiology                         •  What is the true recurrence rate and risk for chronic
           Large epidemiologic studies or registry analysis could  pain after Shouldice repair?
           result in new insights in the incidence of groin hernia. The  •  Is only SAC resection in young patients with an L1
           identification of modifiable life style and socio-occupa-  inguinal hernia a safe procedure in terms of recurrence
           tional factors contributing to development of primary and  rate?
           recurrent inguinal hernia could help hernia surgeons in the  •  Is there a significant difference in results of tissue
           future to further tailor surgical management.         (Shouldice) repair between an indirect and a direct
                                                                 hernia?
           Pathophysiology                                    •  Are the outcomes after repair with a self-adhesive mesh
           It is becoming increasingly clear that the extracellular  comparable with a repair with a flat mesh for
           matrix and matrix metalloproteinases play a significant role  Lichtenstein?
           in the pathogenesis of abdominal wall hernias. Further  •  Do TEP and TAPP truly have equal results to each
           investigation into biomarkers which mirror its activities as  other?
           well as strategies and methodologies to correct abnormal-  •  What are the advantages of the use of Prolene Hernia
           ities could dramatically affect the incidence and treatment  System (PHS) or UltraPro Hernia System (UHS)
           of abdominal wall pathologies. Interdisciplinary collabo-  compared to Lichtenstein and TEP, TAPP?
           rative research with basic science will be necessary to  •  What are the long-term recurrence rates after inguinal
           properly investigate this complex environment.        hernia repair with PHS or UHS? Are these results
                                                                 significantly better to justify the use and subsequent
           Classification                                         scarring  of  both  the  anterior  and  posterior
                                                                 compartment?
           Hernia classifications contribute to the possibility to com-
                                                              •  There is a need to design a large RCT comparing
           pare and evaluate study outcomes and subsequent man-
                                                                 laparo-endoscopic and Lichtenstein repair in primary
           agement strategy. Which classification system are the most
                                                                 unilateral inguinal hernia repair in male patients by
           suitable remains unknown. The EHS classification system
                                                                 surgeons who are experts in both these respective
           is a simple system and easy to use. Future research should
                                                                 techniques.
           evaluate what the relevance of the EHS groin hernia clas-
           sification is.
                                                              Individualization in treatment options
           Indications for surgery                            For many years now, the gold standard for inguinal hernia
           Watchful waiting (WW) has been a suggested management  surgical treatment is a mesh repair. The mesh repair can be
           strategy in male patients with a minimal or asymptomatic  performed open or laparoscopically. Whether there is still
           inguinal hernia. Some aspects of WW need to be analyzed  an indication for non-mesh repair, or when a mesh repair
           to fully establish its true value. Is a watchful waiting  needs to be done open or laparoscopically remains to be
           strategy ultimately cost-effective, considering high cross-  definitely determined. There is no uniform technique
           over rates due to symptom development? What are the risk  applicable to all patients. Hernia surgeons individualize,
           factors for developing symptoms such as pain or incar-  based mostly on their own experience. Scientific founda-
           ceration in untreated male patients with a minimal symp-  tion is lacking. The essential question is: When do we
           tomatic or asymptomatic inguinal hernia? What is the best  individualize and does a tailored approach result in
           timing for male patients with a minimal symptomatic or  improved quality and outcomes? Scenarios where indi-
           asymptomatic inguinal hernia to plan surgical repair in  vidualization might be in place are:
           terms of cost-effectiveness? A large randomized controlled
           trial with long follow-up would be appropriate to answer  •  Which surgical technique should be used in patients
                                                                 with an inguinal hernia with the following character-
           this question.
                                                                 istics: high preoperative pain, smoking, collagen dis-
                                                                 ease, obesity, ascites, physical active or elderly?
           Surgical treatment of inguinal hernia
                                                              •  Which surgical technique should be used in patients
           There are many of studies performed on surgical tech-
                                                                 with an inguinal hernia with the following character-
           niques in inguinal hernia. However, not all techniques are
                                                                 istics: small indirect, (large) medial or large lateral
           equally well evaluated and there is still need for further
                                                                 hernias, non-reducible hernias, incarcerated hernias or
           research. Randomized controlled trials in centers where the
                                                                 strangulated hernias?
           various surgical techniques are mastered are ideal to
           address the following issues:


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