Page 175 - Pharmacology Mnemonics and Short Notes

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Uses discussed already Substitute of aspirin  especially
in children with viral infection

Toxicity of Acetaminophen

 Therapeutic dosage  negligible toxicity

 Overdose or in patient with liver impairment  Hepatotoxic drug
toxic metabolites produced by phase I reaction if substrates of
phase II reaction (acetate and glucouronate) are lacking

 Antidote  Acetyl cysteine

Drugs used in treatment of Gout

Drugs used in Gout

Acute Chronic

Xanthine
Glucocorticoid
NSAIDs Colchicine Uricosurics oxidase
s
inhibitors

microtubule
Dexamethaso
Indomethacin synthesis Probenicid Allopurinol
ne
inhibitor

Treatment strategies

Gout  increase uric acid in serum  deposition of Uric acid crystals in

Joints  inflammation

Treatment strategies will be
Contents  Reduce inflammation  Colchicine, NSAIDs or Glucocorticoids

Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman