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 Accelerate renal excretion of uric acids  uricosuric drugs
Probenicid and Sulfinpyrazone

 Reducing conversion of purines into uric acid  by xanthine
oxidase inhibitors  allopurinol

indian • indomethacine

Coli (player) • cochicine

provided • probenicid

aalu • allopurinol

to salman • Sulfinpyrazone

Anti-inflammatory drugs

NSAIDs such as indomethacin  inhibit inflammation of acute gouty

arthritis  reduce prostaglandin synthesis and phagocytosis by
macrophages.

Colchicine  inhibit microtubule assembly  reduce migration of
leukocytes and phagocytosis. Reduce inflammation

Glucocorticoids preferred for treatment of acute gouty arthritis

Uricosuric Drugs

90% of uric acid is reabsorbed in proximal convoluted tubule

Uricosuric drugs  prevent reabsorption of uric acid in PCT
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Pharmacology Mnemonics and Short Notes By Muhammad Ramzan Ul Rehman