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Klingeborn et al. Page 44
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Figure 5. Exosomal proteins highly co-enriched with the exosome-specific marker Syntenin-1,
differ markedly between apically and basolaterally released exosomes in a polarized RPE cell
culture model
Note that in these highly stringent exosome-specific proteome datasets, only 12 proteins are
released in exosomes from both sides, emphasizing the exceptional directionality in EV
release from polarized RPE monolayers (Klingeborn et al., 2017). Permission pending.
Author Manuscript
Author Manuscript
Prog Retin Eye Res. Author manuscript; available in PMC 2018 July 01.
