Page 105 - Medicine and Surgery
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         BLUK007-03  BLUK007-Kendall  May 25, 2005  17:29  Char Count= 0












                              or      or  +/−  Despite  mortality  and  or    or                 (e.g.  better  of
                          Erythromycin,  azithromycin,  clarithromycin  doxycycline  Erythromycin,  azithromycin,  clarithromycin  ciprofloxacin  rifampicin  these  ∼20%  Cefuroxime  gentamicin  Ciprofloxacin  ceftazidime  Metronidazole  i.v.  Hi-dose  cotrimoxazole  pentamidine  i.v.  pneumonia  viral  development




                                                                                                 severe  Asia,  the  with
                                                                                          by
                                                                                be
                                                                  the
                          complement  specific  Immunofluorescent  or  sputum  lavage.  with  culture,  blood  colonise  a  as  perihilar  glass  ground  may  but  disease.  early  ground-glass  bronchial  induced  diagnosis  by  or  in originating  recognised


                          –  antibody  tests:  for  Urine  antigen.  on  bronchial  lobar  consolidation  cavitation  and  does  it  airway  commensal  –  CXR  ‘butterfly’  shadowing.  in  shadowing,  or  for  staining  immunofluorescence
                          Serology  fixing  Rapid        tests  Extensive  Sputum  but  upper  Typical  normal  shows  CT  lavage  sputum  silver  commonly  increasingly


                                                                                                 most  are  and
                                                      lesions
                                                                              is
                          untreated  fatal  is  and  (raised  are           ∼10%  prophylaxis  with  influenza,  infants  as

                          If  infection  LFTs  failure.  cavitating  abscesses  now  e.g.        H 5 N 1  or  well  as
                          Endocarditis.  chronic  Hypoalbuminaemia  abnormal  transaminases)  common.  renal  Acute  cause  lung  –  Mortality  Long-term  required,  co-trimoxazole  SARS  as  elderly


                                                      May
                                                                                                 such  the  in diagnostics. Any respiratory virus and particularly respiratory syncitial virus and those of the Herpes family (most commonly Cytomegalovirus) may cause pneumonia in the immunosuppressed

                          which  it  if  prodromal  confusion  without  purulent,   Fine  to     pathogens  common such as organ transplant and HIV patients. Influenza A may cause a solely viral pneumonia, but is often complicated by secondary bacterial infection, especially Staph. aureus.

                          illness  pneumonia  with  often  lesions  CXR  diagnostic  the  are  of:  3  of  day  cough,  diarrhoea  leucocytosis  Hyponatraemia  severe  upset,  sputum  redcurrant  pneumonia  cough,  dry  breath,  of  Marked  particularly  exertion.  nothing  or  auscultation.  viral  new  are
                          Influenza-like  a  causes  persists,  multiple  main  The  indications  presence     2–10  A  period     Dry  or    Lymphopenia  marked     onset, Sudden  systemic  mucoid  (classically  Lobar  jelly).  fever,  High  shortness  tachycardia.  hypoxia,  following  crackles  on  find  to  due  pneumonias  Viral






                          overall  people  water  source  2:1  of  disease,  patients.  to       epidemics sporadic  adults.

                          cases   fit  from  cases  in  Females  history  a  lung  alcohol  malignancy  cystic  due  e.g.  Diabetics  common  AIDS  and  of  healthy  in
                          of                Outbreaks  immuno  compromised  individuals  with  or  or  and  opportunistic  in  count  immunosuppressed
                          1%      Previously  infected  system.  Sporadic  unknown  Males:  heart  diabetes,  excess  Nosocomial,  fibrosis  neutropenic  Aspiration,  stroke.  most  infection  (CD4  <200/mm 3 )  patients  exception  uncommon
                          Only                        Elderly               The                  the  is
                                                                                                 With
                          burnetii  fever)  pneumophilia                –     (PCP)  Pneumocystis  pneumonia:  adenovirus)


                          Coxiella  (Q  Legionella    Klebsiella  Pseudomonas  aeruginosa  Anaerobes  Bacteroides  Pneumocystis  jiroveci  (previously  carinii)  Viral  by  caused












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