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376   Chapter 3

            COMPUTED TOMOGRAPHY

  VetBooks.ir                                                  Mathieu Spriet





            INTRODUCTION                                       patient remains stationary during image acquisition as
                                                               the gantry itself travels over the area to be imaged. The
              Computed tomography (CT) is a cross‐sectional    horse can be positioned on a standard equine table, sim­
            imaging technique, relying similarly to radiography, on   plifying the logistics.
            differential X‐ray attenuation by the tissues being   In addition to the table design, the gantry diameter is
            imaged. Images are acquired as slices of the anatomy of   a limitation to the range of body areas that can be
            the imaged subject, providing three‐dimensional (3D)   imaged. Most classic human gantries have a diameter of
            information. These slices of anatomy are obtained by   55–75 cm, limiting applications in horses to the distal
            rotating an X‐ray generator around the imaged body   limbs and head to cranial neck (typically to the level of
            area and recording attenuation of the X‐ray beam at   the third or fourth cervical vertebrae). Larger gantries
            multiple different angles. The attenuation data are then   have been designed for bariatric human patients with a
            digitally processed to reconstruct an image.       diameter up to 90  cm. These systems provide the ability
              The imaging principles, relying on X‐ray attenuation,   to image larger body areas such as the equine caudal
            are similar to radiography. CT is excellent at imaging   neck and stifles. Most recently scanners designed for
            bones, with dense bones appearing white (hyperattenu­  intraoperative use in human neurosurgery even offer
            ating), whereas gas will show up black due to a lack of   larger gantries, with a diameter over 100  cm.
            X‐ray attenuation. Soft tissue structures will display an   The recent development of cone‐beam CT technology
            intermediate (gray) opacity. Based on calibration of the   brought versatility in the design of scanners. Cone‐beam
            attenuation data, CT is better than radiography at iden­  scanners use a flat panel detector, similar to a digital
            tifying small differences in tissue density. For this rea­  radiography plate. This allows modification of the con­
            son, tendon, synovial fluid, and connective tissue can be   figuration of the classic gantry with asymmetric shape
            differentiated on CT, while they typically have the same   and larger aperture. A robotic arm CT system has also
            opacity on radiographs. CT also presents the advantage   been developed: the classic gantry has been replaced by
            over radiographs to eliminate superimposition of struc­  two robotic arms, one carrying the X‐ray generator and
            tures. The combination of the increased contrast resolu­  one the detector plate. This potentially provides more
            tion and abolition of superimposition explain why CT   versatility for scanning standing horses and imaging
            detects lesion not recognized on radiographs.      larger areas. Cone‐beam CT provides an excellent spa­
              CT has been used in the horse since the late 1990s,   tial resolution, but limitations exist regarding contrast
            mostly for head and distal limb imaging. Due to techno­  resolution and sensitivity to motion.
            logical progress, CT cost and availability have greatly   As an X‐ray‐based imaging technique, the generator
            improved in the recent years. Also modification of the   current intensity (mA) and voltage (kV) are important
            size and configuration of the scanners have led to the   technical parameters for CT similar to radiography.
            development of new clinical applications, such as imag­  Additional parameters, including slice thickness, recon­
            ing of the neck and more proximal areas of the limbs.  struction algorithm, field of view, and matrix size, are
              In this chapter, the basic principles of CT will be   also important to understand the optimization of CT
            described along with the different systems that are avail­  image quality. Depending on the type of tissue imaged,
            able. The clinical applications of CT will be limited to   the technique will be different.
            musculoskeletal imaging due to the focus of this publi­  In order to optimize images for bone, it is important
            cation. Imaging of the equine head, although a major   to have a high spatial resolution and sharp edges. This is
            indication for CT imaging, will not be covered.    typically achieved with using thin slices, an edge
                                                               enhancement algorithm, a small field of view, and a
            EQUIPMENT AND PRINCIPLES OF CT                     large matrix (Figure 3.194). The slice thickness in stand­
                                                               ard multislice CT is typically less than 1  mm, classically
              Classic CT scanners consist of a gantry, containing a   0.65  mm. The in‐plane spatial resolution is governed by
            rotating X‐ray generator and an array of detectors, and   the matrix size and the reconstruction field of view.
            a table translating the patient through the gantry for   Most CT images will use a 512  ×  512 matrix. The pixel
            image acquisition. Obviously, the standard human table   size is obtained by dividing the field of view by the
            needs to be adapted to the size and weight of the equine   matrix size. This is important to keep in mind as most
            patient. This is typically accomplished by adding a large   classic  CT  scanners  can  image  a  50‐cm  field  of  view;
            table top over the human table but presents a techno­  however in the configuration the pixel size will be ~1  mm
            logical challenge as the patient needs to be moved pre­  (500/512). Reducing the field of view to 25  cm, which is
            cisely through the gantry during image acquisition.   usually enough to cover the limb anatomy to image, per­
            A few commercial solutions are available, but many sys­  mits  bringing  the  pixel  size  to  0.5  mm  (250/512),
            tems rely on custom‐made tables. An interesting varia­    doubling  the  in‐plane  spatial  resolution.  The  edge
            tion in the scanner design is the configuration of a few   enhancement algorithm is a filter that is applied to the
            systems having a translating gantry. In these systems, the   acquired  data  to  help  make  the  image  edges  more
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