Page 163 - BSAVA Guide to Pain Management in Small Animal Practice
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BSAVA Guide to Pain Management in Small Animal Practice



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                  Splenic mass in a Labrador Retriever
                3  associated with an acute haemoabdomen.

           pain may be associated with the presence of
           the tumour itself or may be a complication of   Pathological fracture in the femoral neck of
           cancer surgery  e.g. phantom pain after limb or         a Leonberger at the site of a primary bone
           digit amputation . It can also be associated with   tumour  osteosarcoma .
           the use of ad uvant therapies or the presence of
           chronic co morbidities  see above .    ■   Visceral pain arises from stretching,
              Cancer associated pain may initially be acute   distension or obstruction of viscera.  his type
           but if a tumour is allowed to reach an advanced   of pain is poorly locali ed and is associated
           stage before pain is recogni ed and managed   with a dull, deep, cramping and aching
           e ectively, a chronic pain state of varying   sensation  see  igure 7.   for examples of
           severity may develop   aynor,      . It is widely   tumours that can cause visceral pain .
           recogni ed that cancer pain therefore more often   ■    Neuropathic pain occurs due to a lesion or
           mimics a chronic rather than an acute pain   disease that a ects the tissues of the
           model  Christo and  a loomdoost,      .   somatosensory nervous system itself.  his
              A patient with chronic cancer associated   type of pain may occur through direct tumour
           pain may also experience episodes of      compression or in ltration of nerves or nerve
           breakthrough pain. An example would be the   roots or may be associated with tumour
           occurrence of a pathological fracture at the site   treatment. It is associated with a burning,
           of a primary bone tumour   igure  .   . A period   shooting or electric shock like sensation.
           of weeks of chronic pain may precede an acute
           pain episode associated with collapse of the    wo other important concepts in the
           cortical bone.                         pathophysiology and management of cancer
                                                  associated pain are the processes of wind up
           Type and localization                  and sensiti ation.  ind up occurs due to
                                                  persistent nociceptive input to the spinal cord
           Cancer associated pain may be somatic,
           visceral or neuropathic in origin   aynor,    8 .   leading to potentiation of sensory pathways and
            ur understanding of the associated pain   contributes to sensiti ation. Sensiti ation is
           sensations is inferred from human reports and   associated with a state of pain hypersensitivity
           by examining an animal s behaviour.     termed allodynia and hyperalgesia .
                                                      he complexity of managing cancer
           ■   Somatic pain arises through tumour  or   associated pain therefore re ects the need to
              treatment associated damage to bones,   take into account its origin, intensity, duration
               oints, muscle or skin; it is locali ed,   and the occurrence of additional factors
              constant and throbbing or aching in nature.  including wind up and sensiti ation.

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