Page 161 - BSAVA Guide to Pain Management in Small Animal Practice
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BSAVA Guide to Pain Management in Small Animal Practice



        VetBooks.ir  ■   Vasculitis
               ypertrophic osteopathy
           ■
              Necrolytic migratory erythema
           ■
           ■   New tumour formation.
           Therapies and associated side

           Cancer therapy and speci cally treatment
           related side e ects, can lead to pain. A clinician
           should provide multimodal pre emptive
           analgesia whenever possible according to the
           clinical circumstances   aynor,    8 .
              Surgery, performed with either therapeutic
           or diagnostic intent  e.g. tumour biopsy  causes         Acute radiation therapy side e ect
                                                          mucositis  in the oral cavity of a  almatian
           pain.  ypically, surgery is associated with acute   following treatment for a soft tissue tumour.
           pain, which follows bodily in ury and tends to be
           self limiting following appropriate healing.    Bone necrosis
              Ad uvant therapies used in cancer   ■
           management include radiotherapy and    ■    istula formation.
           chemotherapy. Although advances in modern   Chemotherapy can be associated with pain
           treatment planning systems allow for targeted   through the drug infusion itself, if extravasation
           radiation treatment and a clinician may choose   in ury occurs with certain cytotoxics   igure
           appropriate dosing and fractionation, both    .   .  rug induced neuropathies, although
           acute and late side e ects can occur, which can   rarely signi cant clinically, are reported with
           result in signi cant pain   aynor,      .  ue to   cisplatin, vincristine, and vinblastine treatment
           the advances in modern planning systems    Cudden,      .
           allowing for targeted radiation and also
           appropriate dosing or  fractionation , side e ects   Inference from human reporting
           are controlled during treatment; however, both    he similar biological behaviour of neoplasia
           acute and late side e ects are described.  between species and treatment methods
              Acute e ects usually occur     weeks after
           starting de nitive therapy, and resolve within   employed suggests that tumours or inter
               weeks.  hese may include, depending on   ventions associated with pain in humans are
           the site of radiation treatment        likely to be associated with pain in dogs and cats.
                                                     In  igure  .  , examples of some types of
           ■   Skin reaction, either moist or dry   cancers that occur in companion animals and
              des uamation                        which may be associated with signi cant pain
           ■    ral mucositis following radiation therapy   are listed   an,      .
              for nasal or oral tumours   igure 7.
           ■   Proctitis.
              Late e ects, which occur months to years
           after treatment is completed, are permanent,
           irreversible changes.  hese occur more
           commonly following hypofractionated or
           palliative radiation protocols and include

           ■    cular changes, such as keratocon unctivitis
              sicca                                       ull thickness cutaneous necrosis at the
           ■   Bowel strictures                          site of extravasation of a chemotherapy
           ■   Soft tissue  brosis                drug in a  reyhound.

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