Page 2432 - Cote clinical veterinary advisor dogs and cats 4th
P. 2432

1204  Blood Type Groups, Dogs                                                                       Bradycardia



            Blood Type Groups, Dogs                              Bone Diseases, Congenital
  VetBooks.ir  Dog Erythrocyte Antigen (DEA) Systems and Blood   Congenital Skeletal Disorders of Small Animals


            Types
                                                                 Generalized Bone Malformations
                        Estimated                                  Osteopetrosis—dense bones
                        Population                                 Osteogenesis imperfecta—osteopenia and bone fragility
            Antigen     Prevalence    Comment                      Mucopolysaccharidosis—lysosomal enzyme defects
                                                                   Dwarfism—osteochondrodysplasias (Scottish fold) and pituitary
            DEA 1.1     62%           DEA 1.x antigens are most    Congenital hypothyroidism
                                      associated with ITR          Retained cartilage cores
            DEA 1.2     2%                                         Craniomandibular osteopathy
                                                                   Multiple cartilaginous exostoses
            DEA 1.3     0.1%                                       Avascular necrosis of the femoral head
            DEA 3       5%            Most likely in greyhounds and   Malformations of Individual Bones
                                      Japanese-bred dogs           Hemimelia—radial or tibial agenesis
                                                                   Congenital amputation—absence of distal limb portion
            DEA 4       98%           ITR to antigen extremely rare due   Phocomelia—missing segment of limb
                                      to high prevalence
                                                                   Amelia—absence of complete limb
            DEA 5       15%           Most likely in greyhounds and   Malformations of Bone Combinations
                                      Japanese-bred dogs
                                                                   Syndactyly—fused digits
            DEA 6       96%           No commercial typing system for   Polydactyly—extra digits
                                      recognition                  Ectrodactyly—split or lobster claw deformity
            DEA 7       40%-55%       Can be found unassociated with   Adapted from Ettinger S, Feldman E: Textbook of veterinary internal medicine, ed 6, St. Louis,
                                      RBC                       2005, Saunders, p 1970.
            DEA 8       20%-40%       No commercial typing system for
                                      recognition
            Dal         98%           Lack of Dal in Dalmatians (11.7%),
                                      shih tzus (57.1%), and Doberman
                                      pinschers (42.4%) increases risk of
                                      transfusion reaction in these breeds

           ITR, Immunologic transfusion reaction; RBC, red blood cell.







            Bradycardia



            Causes of Bradycardia in Dogs and Cats
             A.  Arrhythmias                                     F.  Vagal tone high: normal
              1.  Second-degree AV block                          1.  Brachycephalic breed
              2.  Third-degree AV block                           2.  Athletic animal at rest
              3.  Sick sinus syndrome/sinus node dysfunction      3.  Sleep
              4.  Atrial standstill (hyperkalemia, atrial myopathy)   G.  Vagal tone high: abnormal
             B.  Hypothermia                                      1.  GI disturbances
             C.  Hypothyroidism                                   2.  Upper respiratory obstruction (e.g., foreign body, laryngeal paralysis,
             D.  Organophosphate toxicosis                          elongated soft palate, laryngeal collapse, airway edema, mass, anesthetic
             E.  Pharmacologic (e.g., due to beta-blockers, calcium channel blockers, digitalis,   circuit problem)
              opiates, alpha-2 agonist drugs)                     3.  Neurologic lesions (central and severe: usually comatose patient)
           AV, Atrioventricular; bpm, beats per minute; GI, gastrointestinal.
           NOTES: First-degree AV block does not affect the heart rate.
           In critically ill or anesthetized animals, an acute transition from tachycardia to bradycardia may indicate an immediate transition to cardiac arrest.
           Definition of bradycardia in the clinical setting: heart rate < 60 bpm (large-breed dogs), < 70 bpm (medium-breed dogs), < 90 bpm (small-breed dogs), < 130 bpm (cats).












                                                     www.ExpertConsult.com
   2427   2428   2429   2430   2431   2432   2433   2434   2435   2436   2437