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Central Nervous System Disorders: Multifocal/Diffuse Cerebrospinal Fluid Abnormalities 1205.e1

Central Nervous System Disorders: Multifocal/Diffuse
VetBooks.ir Degenerative Inflammatory—Infectious Inflammatory—Noninfectious

Lysosomal storage disease
Granulomatous meningoencephalitis
Mitochondrial encephalopathy Viral Distemper Meningoencephalomyelitis of unknown origin
Organic aciduria Herpesvirus Eosinophilic meningoencephalitis
Cognitive dysfunction syndrome Parvovirus Necrotizing encephalitis
Anomalous Parainfluenza Necrotizing leukoencephalitis
Chiari malformation/caudal occipital malformation FIP Necrotizing meningoencephalitis
syndrome FIV Breed-associated necrotizing encephalitis: pug,
Intracranial arachnoid cyst Bacterial Maltese, Yorkshire terrier
Hydrocephalus Bacterial encephalitis Nonclassified
Steroid-responsive meningoencephalitis
Tetanus
Metabolic Fungal
Hepatic encephalopathy Cryptococcosis Idiopathic
Hypoglycemic encephalopathy Blastomycosis Dysautonomia
Electrolyte-associated or osmolar encephalopathy Coccidioidomycosis Toxins
Endocrine disorder–associated encephalopathy Candidiasis Bromethalin
(e.g., hypo- or hyperthyroidism) Aspergillosis Marijuana
Neoplastic Protozoal Metaldehyde
Primary brain tumors Toxoplasmosis Tricyclic antidepressants
Metastatic/multifocal brain tumors (e.g., Neosporosis Vascular Disease
lymphoma) Parasitic Intracranial hemorrhage
Nutritional Toxocara Thromboembolism
Cuterebra
Thiamine deficiency Rickettsial Hypertension
Spinal hemorrhage
RMSF
Ehrlichia Differentials, Lists, and Mnemonics
Unclassified
Protothecosis
CNS, Central nervous system; FIP, feline infectious peritonitis virus; FIV, feline immunodeficiency virus; RMSF, Rocky Mountain spotted fever.
Modified from Ettinger S, Feldman E: Textbook of veterinary internal medicine, eds 6 and 7, St. Louis, 2005 and 2010, Saunders.

Cerebrospinal Fluid Abnormalities

CSF Determinations and Diseases of the Nervous System
DISEASE
Determination Meningitis Parenchymal Disease
Bacterial disease: suppurative inflammation Tissue necrosis: neoplasia, degenerations
Viral disease: nonsuppurative inflammation
Physical Turbid, clot Clear, colorless
Cytologic (WBC)
Quantitative Large increase: > 100/cmm Small increase: < 100/cmm
Differential Mostly neutrophils Mostly mononuclear cells
Chemical
Protein
Quantitative (total) Large increase: > 100 mg/dL Small increase: < 100 mg/dL
Glucose: normally about 80% of blood level Normal or decreased to below 50% of blood level Normal
cmm, Cubic millimeter; CSF, cerebrospinal fluid; WBC, white blood cell.
Modified from de Lahunta A: Veterinary neuroanatomy and clinical neurology, St. Louis, 1983, Saunders.

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