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1018   PART VIII   Reproductive System Disorders



                   TABLE 57.3
  VetBooks.ir  Puppy Biochemical Parameters From Birth to Approximately 8 Weeks of Age  WEEKS 4-5    WEEKS 7-8



                                        DAYS 1-3            DAYS 8-10           DAYS 28-33           DAYS 50-58

             Albumin (g/dL)             1.76-2.75            1.71-2.5            2.17-2.97            2.38-3.22
             ALP (U/L)                   452-6358            195-768              153-490             153-527
             ALT (U/L)                   9.1-42.2             4.1-21.4            4.3-17.4            10.3-24.3
             Bilirubin (mg/dL)          0.04-0.38            0.01-0.18           0.02-0.15            0.01-0.11
             BUN (mg/dL)                29.5-118             29.1-66.7           13.1-46.2            16.8-61.4
             Calcium (mg/dL)            10.4-13.6            11.2-13.2           10.4-13.2            10.8-12.8
             Cholesterol (mg/dL)          90-234             158-340              177-392             149-347
             Creatinine (mg/dL)         0.37-1.06            0.28-0.42           0.25-0.83            0.26-0.66
             GGT (U/L)                   163-3558               —                   —                    —
             GLDH (U/L)                  1.8-17.0             0.2-17.7            1.2-9.0              1.6-7.3
             Glucose (mg/dL)              76-155             101-161              121-158             122-159
             TP (g/dL)                   3.7-5.77            3.26-4.37           3.71-4.81            4.04-5.33
             Triglycerides (mg/dL)        45-248              52-220               36-149              39-120
             Phosphorus (mg/dL)         5.26-10.83           8.35-11.14          8.66-11.45           8.35-11.14

            Adapted from Center SA et al.: Effect of colostrum ingestion on gamma-glutamyltransferase and alkaline phosphatase activities in neonatal
            pups. Am J Vet Res 52(3):499-504, 1991; Kuhl S et al.: Reference values of chemical blood parameters for puppies during the first 8 weeks
            of life, Dtsch Tierärztl Wschr 107:438-443, 2000; Harper EJ et al.: Age-related variations in hematologic and plasma biochemical test results
            in Beagles and Labrador Retrievers. J Am Vet Med Assoc 223(10):1436-1442, 2003.
            From von Dehn B: Pediatric clinical pathology. In Davidson AP (ed) Pediatrics. Vet Clin of North Amer: Small Animal Practice.
            31;44(2):205-219, 2014.





                   TABLE 57.4

            Puppy Biochemical Parameters Up to 12 Months of Age

                                              2-3 MONTHS                4-6 MONTHS                 7-12 MONTHS
             Albumin (g/dL)*                  2.6-3.7                   2.6-3.7                    2.6-3.7
             ALP (U/L)                        88-532                    126-438                    4-252
             ALT (U/L)                        ≤29                       ≤32                        5-45
             Amylase (U/L)*                   ≤1683                      ≤1683                     ≤1683
             AST (U/L)                        7-19                       3-23                      2-26
             Bilirubin (mg/dL)                0.01-0.13                  0.01-0.13                 ≤0.3
             BUN (mg/dL)*                     9.8-37.3                   9.8-37.3                  9.8-37.3
             Calcium (mg/dL)                  10.4-13.6                  10-13.2                   10.4-12
             Chloride (mEq/L)*                99-120                     99-120                    99-120
             Cholesterol (mg/dL)              99.6-499.6                 99.6-499.6                135-278
             CK (U/L)                         31-255                     40-192                    ≤134
             Creatinine (mg/dL)               0.39-0.49                  0.27-0.88                 0.21-0.89
             GGT (U/L)                        ≤6.2                       ≤4.3                      ≤3.2
             Globulins (g/dL)                 1.9-2.5                    2.2-3.5                   2.2-4.5
             Glucose (mg/dL)                  97.1-166.2                 97.1-166.2                76-119
             GLDH (U/L)                       1.6-9.6                    1.9-8.7                   1.2-8.0
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