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CHAPTER 57   Neonatology and Pediatrics   1023





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                   FIG 57.20
                   Bottle-feeding apparatus, Bull Mastiff litter.


            25% to 50% with water or a balanced crystalloid solution.
            Neonates should gain weight steadily from the first day after
            birth (a transient mild loss from birth weight is acceptable   FIG 57.21
            on day 1), with puppies gaining 1 to 3 g/day/lb (2.2 kg) of   Esophagram, 14-day-old neonate with regurgitation of milk
            anticipated adult weight and kittens 50 to 100 g/wk. Neona-  through the nares. Congenital megaesophagus.
            tal weights should be recorded daily for the first 2 weeks,
            then every 3 days until 1 month of age. Healthy, well-  and bronchopneumonia. Situs inversus can also be present.
            nourished neonates are quiet and sleep when not nursing.   The long-term prognosis, even with supportive therapy, is
            The normal neonatal weight gain is an increase of 5% to 10%   poor. Neonatal dyspnea with evidence of gastrointestinal
            body wt/day. The limited size of neonatal stomach, and pro-  disorders  can occur secondary to  congenital  peritoneo-
            pensity for regurgitation/aspiration if overdistension from   pericardial or pleuroperitoneal diaphragmatic  hernias.
            overfeeding occurs, necessitates multiple small feedings   Thoracic wall abnormalities, such as pectus excavatum, a
            around the clock. Most commercial milk replacers deliver   sternal intrusion into the thorax, can cause dyspnea and is
            approximately 1.0 kcal/mL; maximum comfortable stomach   variably associated with poor growth. Surgical correction
            capacity approximates 4 mL/100 g body weight.        of thoracic wall abnormalities is indicated if the neonate is
                                                                 symptomatic once adequate body size is attained. Reports
                                                                 of a neonatal respiratory distress syndrome secondary to a
            PEDIATRIC SYSTEMIC ABNORMALITIES                     deficiency of surfactant exist; affected neonates died within
            Cardiovascular Disorders                             5 days of age. Surfactant deficiency secondary to prematurity
            Ventricular septal defects, mitral valve disorders, and   is predictably problematic. Proper timing of elective cesar-
            arteriovenous fistulas are the most common congenital   ean sections is vital to avoid premature delivery of surfactant
            cardiac defects. Cardiac defects can arise from environmen-  deficient neonates. The administration of corticosteroids to
            tal stress, infection, or intoxication of the dam; however, the   term  pregnant  bitches  does  not  result  in  the  formation  of
            heritability of many has been documented. Clinical signs are   surfactant (Sipriani et al., 2009). Radiography of the term
            often not apparent until after weaning, although affected   pregnant bitch should permit visualization of fetal dentition
            neonates may not be as vigorous as normal littermates. Accu-  (Fig. 57.22).
            rate cardiac auscultation should be possible at and after 6 to
            8 weeks of age; echocardiography is the preferred mode of   Musculoskeletal Disorders
            evaluation once adequate pediatric size is attained, usually at   Neonates can be born with hind limb hyperextension of
            3 to 4 months of age.                                unknown etiology; because their joints are lax, simple ban-
                                                                 daging in a flexed position for 2 to 3 days can resolve the con-
            Respiratory Disorders                                dition (Fig. 57.23). Puppies with noticeable flattening of the
            Primary ciliary dyskinesia, the rare immotile cilia syn-  sternum at 3 to 4 weeks of age are called “swimmer puppies”
            drome, should be suspected in neonates exhibiting persis-  by breeders. Swimmer puppies fail to develop normal step-
            tent or recurrent mucopurulent nasal discharge, coughing,   ping  ambulation at  14  to  21  days of life,  moving  instead
            and abnormal breath sounds without other demonstrable   by paddling their limbs laterally and caudally. Compression
            cause. The presence of a cleft palate, persistent right aortic   and deformation of the sternum and thorax occurs con-
            arch, and congenital megaesophagus should be ruled out   currently (Fig. 57.24, A). Obese puppies from small litters,
            (Fig. 57.21). Abnormal mucociliary transport and neutro-  raised on slippery surfaces, are predisposed. Treatment
            phil function result in chronic rhinitis, tracheobronchitis,   should be instituted immediately upon diagnosis, consisting
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