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Lameness of the Distal Limb  451


             any of these shoes enhances break‐over, thus reducing   meglumine, phenylbutazone, and firocoxib are used
             the stress on the DDFT. The goals of any of these shoes   most commonly, and all should be effective in reducing
  VetBooks.ir  reduce the forces acting on the navicular bone by the   ease that were treated with 1.1 mg/kg of flunixin meglu-
                                                                 inflammation and lameness. Horses with navicular dis-
             should be to ease break‐over, support the heels, and
                                                                 mine or 4.4 mg/kg phenylbutazone once daily for 4 days
             DDFT.
               Heel elevation has been shown to decrease tension in   showed  significant  reduction  in  lameness  scores  for
             the DDFT, reduce pressure applied to the navicular   24  hours after the last dose compared with baseline
             bone, reduce the load to the forelimbs, and reduce the   and horses treated with saline.  The clinical responses
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             stresses on the hoof capsule (Figure 4.16). 96,98,102,132  The   between flunixin meglumine and phenylbutazone were
             heels are supported for a greater proportion of the stride,   similar and suggest that once‐daily dosing of NSAIDs
             and the wedge tends to increase the weight transferred   should be effective to control pain in the majority of
             through  the  heels.  A  recent  study  that  quantified  the   these horses.
             pressure distribution across the palmar surface of the   NSAIDs are often used for pain relief if the horse is
             navicular bone documented that the maximum pres-    severely lame or if the horse needs to continue working
             sures exerted by the DDFT corresponded to the areas of   through the initial treatment period. Phenylbutazone is
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             known navicular pathology.  However, raising the    usually used most frequently because it is less expensive
             heels by 5° and 10° only redistributed the pressures on   than flunixin meglumine. It is usually given at a dose of
             the navicular bone, suggesting that raising the heels may   4.4 mg/kg PO once daily for 7–10 days as the initial
             not be that beneficial in horses with navicular syn-  treatment.  This appears to effectively break the pain
                   128
             drome.  Some clinicians feel that elevated heel shoes   cycle and allows for adjustment to corrective trimming
             offer mixed results and should only be used temporarily   and shoeing.  NSAIDs may be used intermittently
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                                                  106
             especially in horses with DDF tendinopathy.  However,   thereafter if they are permitted for the athletic activity of
             heel elevation alone or when combined with phenylb-  the horse.
             utazone has been shown quantitatively (using a force
             plate)  to  improve  lameness  in  clinical  cases  of horses
             with navicular syndrome.  The disadvantages of rais-  Intrasynovial Medication
                                   102
             ing the heels with the use of pads in horses with under-  Injecting medications into the DIP joint or navicular
             run heels may cause further collapse of the poorly   bursa is often used as an adjunctive treatment for horses
             supported heels, and heel growth appears to be reduced   with navicular disease/syndrome. 3,25,27,75,102,127  Injection
             with wedge pads. 25                                 of medications into the digital flexor tendon sheath
               Egg‐bar shoes and natural balance shoes have not   (DFTS) may also benefit some horses with more proxi-
             been shown to reduce the forces on the navicular bone   mal lesions of the DDFT that are documented with
             as effectively as heel elevation.  However, egg‐bar shoes   MRI.  Deciding when to treat horses with navicular
                                       96
                                                                     106
             increase the length of the toe–heel axis causing the center   disease/syndrome intrasynovially and with what
             of pressure to shift caudally.  Egg‐bar shoes are usually   medication(s) to use is strictly empirical based on many
                                     98
             recommended in cases where the hoof capsule is unsta-  clinical and diagnostic findings. The types of medications
             ble due to shearing or in horses with severely underrun   used are similar to those used to treat OA/synovitis/cap-
             or collapsed heels. The egg‐bar shoe increases the sur-  sulitis in joints at other locations, such as corticosteroids
             face area of contact and the stability of the hoof. The   alone, corticosteroids combined with hyaluronan (HA),
             shoe should be applied so it is clearly visible at the quar-  polysulfated  glycosaminoglycans  (PSGAGs),  or  other
             ters and extends far enough palmarly to cover the   biologic therapies.
             heels. 115,120,121  Natural balance shoes, by their design,   Horses with navicular disease are thought to benefit
             reduce break‐over and if combined with heel elevation   from intra‐articular treatment of the DIP joint by reduc-
             also reduce the forces acting on the navicular bone. See   ing the inflammatory response both within the joint and
             Chapters 8 and 11 for more information on corrective   within the navicular region. 18,85  Studies have demon-
             trimming and shoeing.                               strated that methylprednisolone acetate (MPA) or triam-
               A minimum 2‐ to 3‐week adaptation period is often   cinolone (TA) can diffuse between the DIP joint and
             necessary to achieve pain relief with any type of shoe-  navicular bursa after intra‐articular or intrabursal injec-
             ing. 96,102  In most cases improvement in clinical signs   tion. 18,85  Other studies have documented the benefit of
             after corrective trimming and shoeing should be evident   intrabursal injections in providing substantial but tem-
             within 6 weeks but may depend on the severity of the   porary relief of pain in many horses with navicular dis-
             initial lameness and the specific structures affected.   ease. 27,75,127  The benefit of DIP joint injections is less well
             Severe hoof imbalances may require several shoeing   documented, but anecdotally it is considered effective in
             intervals to achieve a normal hoof conformation, and, in   many horses. 4,25  One study did not find a significant
             some cases, the underrun heels may persist indefinitely.   reduction in lameness after treating the DIP joint with
             Additionally, not all horses respond in the same manner   TA compared to corrective shoeing alone although the
             to  a  particular  shoeing  type,  and  we  as  veterinarians   overall severity of lameness was further reduced follow-
             should remain flexible in using a different type of shoe if   ing treatment.  However, many clinicians use intrasyn-
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             a clinical response is not obtained.                ovial  treatment of  the  DIP  joint  as  part  of  the  initial
                                                                 treatment regimen, together with corrective  trimming
                                                                 and shoeing and phenylbutazone for most horses with
             Nonsteroidal Anti‐inflammatory Drugs
                                                                 navicular disease/syndrome.
               The use of NSAIDs is a common adjunctive treatment   In many horses, especially if advanced imaging can-
             for horses with navicular disease/syndrome. Flunixin   not  be  performed,  there  is  a  stepwise  progression  of
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