Page 413 - Avian Virology: Current Research and Future Trends

404 | Index
IFITM (interferon induced transmembrane proteins) 380–81 Inclusion body hepatitis/hydropericardium syndrome (IBH/HPS) 283,
IFNAR1/IFNAR2 379–80, 382 299, 304, 305, 307, 308
IFNs and IFN signalling 293, 294, 304, 378, 379, 381–82 Infectious bronchitis (IB) 333, 377
IFN type I 379–80 Infectious bronchitis virus (IBV) 133–78
antiviral state in chickens and 381 AI diagnosis and 21
avian adenoviruses and 294, 302, 303, 304 AMPV compared to 124
IAVs and 12–13, 18–19 CAV co-infection with 272
IBDV and 216–17, 218, 220, 222 diagnosis 161–63
IBV and 158 genotype identification 162–63
ILTV and 330 serotype identification 162
NDV and 60, 61, 68–69 virus isolation and identification 161–62
PTX3 and 378 epizootiology 160–61
TLRs and 378–79 evolution 154–55
IFN type II 68–69, 302, 303, 304, 379, 380 genetics and reverse genetics 155–56
IFN type III 379, 380 genome structure and organization 137–38
IFNα 51, 158, 218, 237, 271, 302–3, 378–80, 381–82 geographic distribution of variants 160
IFNβ 51, 152, 158, 216, 218–20, 271, 303, 379–80, 382 history 133–34
IFNγ 379, 380 host cell effects 151–54
AIV/IAVs and 13, 17, 18, 386, 387 activation transcription factor6 151–52
ALV and 237 apoptosis 152
avian adenoviruses and 294, 302–3, 308 autophagy 153
CAV and 271, 274 ER stress and unfolded protein response 151
IBDV and 221 IRE1 152
IBV and 160 MAPK pathway 153–54
ILTV and 331 PERK signalling pathway 151
NDV and 62 immune responses 158–60
NK cells and 382 adaptive immunity 158–59, 385, 386, 387
Th1 cells and 384 cell-mediated immunity 159–60
IFNλ 379, 380 cytokines 160
IgA 385 innate immunity 158, 377, 378, 379, 380, 382, 383
Ig (immunoglobulin) isotypes 384–85 local immunity 159
IgM 384 IRE1 152
IgY 385 morphology 136
IL-1 271, 293 nomenclature 134–35, 164
IL-1β 158, 221, 237, 331, 379, 383 classification 134
IL-2 17, 62, 216, 221, 223, 274 phylogenetic tree 135
IL-4 271, 384 taxonomy of Coronaviridae 134
IL-5 384 non-structural and accessory proteins 143–46
IL-6 68, 139, 154, 160, 221, 223, 237, 271, 379, 383 accessory genes 143
IL-7 223 non-structural proteins 144–46
IL-8 139, 154, 160, 219, 237, 302–3, 330, 383 pathogenesis and clinical features
IL-10 271, 302–3, 331, 382, 384 tissue tropism 157–58
IL-12 13, 17, 223, 271, 302, 382, 383 virulence factors 156–57
IL-13 271, 331, 382, 384 pathogenesis and clinical features 156–58
IL-17 384 prevention and control 163
IL-18 223, 237, 293, 302, 337, 382 exclusion and eradication 163
IL-23 384 vaccination 163 (See also under Vaccines and vaccination)
IL-28/29 379 propagation 136–37, 163
IL-28Rα 380 chicken kidney (CK) cell cultures 137
ILT. See Infectious laryngotracheitis (ILT) embryonated eggs 136–37
Iltovirus 317, 318, 320, 325 other cultured cell lines 137
ILTV. See Infectious laryngotracheitis virus (ILTV) tracheal organ cultures (TOCs) 137
Immediate early (IE) gene expression 346 structural proteins 138–43
Immune complex vaccines 222, 223 E protein 140–41
Immune responses to virus infection. See Avian immune responses to virus host proteins recruited to mature virions 143
infection M protein 140
Immunoglobulin (Ig) isotypes 384–85 N protein 142–43
Immunoreceptor tyrosine-based activation motifs (ITAMs) 382 S protein 138–39
Immunoreceptor tyrosine-based inhibition motifs (ITIMs) 382 viral replication 146–51
Immunosuppression assembly and release 149–51
avian adenoviruses and 301, 302, 304 attachment and entry 146–47
avian reoviruses and 179, 189, 195, 196, 197 cleavage site and size of non-structural proteins 148
CAV and 191, 249, 271–72, 273–74 discontinuous transcriptional model of RNA synthesis 150
IBDV and 211, 212, 215, 216, 217, 221, 222 life cycle 147
MDV and 345, 357 replicase gene and processing scheme of replicase protein
REV and 191, 373 products 148
Imperfect vaccine hypothesis 337 replicase translation and processing 147–48
Importin α/β transport pathway 12 replication and transcription 148–49
Inactivated vaccines 163, 222–23, 388. See also Vaccines and vaccination viral RNA synthesis 149
Inclusion body hepatitis (IBH) 272, 283, 293, 299–308 Infectious bursal disease (IBD) 211, 213, 217, 222–23, 274, 386