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21  Supraventricular Arrhythmias  211

               Prognosis                                           Syncopal episodes are rarely witnessed in cats with AV
  VetBooks.ir  Myocardial damage  usually  progresses,  extending  to   block and dyspnea is a more frequent chief complaint
                                                                  by  owners of cats presented with AV block, whether
               the ventricles. Most animals succumb within 12–18
               months after initial diagnosis, despite pacemaker     congestive heart failure is present or not.
               implantation.
                                                                  Diagnosis
                 Atrioventricular Block                           Electrocardiography
                                                                  There are three types of AV block. With first‐degree
                                                                  AV block, all the atrial impulses are conducted to
               Etiology/Pathophysiology
                                                                  the ventricles, but the PR interval is prolonged on the
               Causes of  AV block  include  excessive  vagal  tone,  AV   ECG (PR >130 ms in dogs, >90 ms in cats). Second‐
               node fibrosis, inflammation or infiltration, and poten­  degree AV block is diagnosed when some P‐waves are
               tially drug toxicity (calcium channel blockers, beta‐  not followed by a QRS complex on the surface ECG.
               blockers, or digoxin). Age‐related fibrodegenerative   Second‐degree AV block is said to be high grade when
               changes in the AV node is the most common cause of AV   the number of atrial impulses that fail to be conducted
               block in dogs.                                     (P‐waves not followed by a QRS complex) to the ven­
                                                                  tricles are more than the number of impulses that are
                                                                  conducted (P‐waves followed by a QRS complex).
               Epidemiology                                       Third‐degree  or complete  AV block is characterized
               Atrioventricular block represents between 60% and 80%   by an absence of conducted P‐waves to the ventricles.
               of the indications for permanent pacemaker implanta­  The ECG displays independent atrial and ventricular
               tion in dogs. The prevalence of clinically significant AV   activities (Figure 21.6).
               block is much lower in cats than dogs. When AV block   Cardiac output is dramatically reduced. In response,
               does occur in cats, it is typically associated with cardio­  the atrial rate, which is under adrenergic tone, is ele­
               myopathy. Fortunately, feline escape rhythms are   vated. Electrical activation of the ventricles is dependent
                 typically  faster than  canine  (80–120 bpm)  and pacing   on an escape rhythm beyond the site of block. In dogs,
               therapy is usually not required.                   the  QRS  complexes  are  generally  wide  and  bizarre  at
                                                                  rates around 20–60 bpm. In cats, the escape rhythm is
                                                                  usually seen as narrow QRS complexes, indicating their
               Signalment                                         origin in the area of the His bundle, and it occurs at a rate
                                                                  of 80–140 bpm.
               Atrioventricular block is more common in geriatric pets.
               Most dogs are above 10 years of age at the time of diag­  Finally, the ventricular rate is regular, unless ventricu­
               nosis. Labradors, cocker spaniels, West Highland white   lar premature beats originating from ischemic areas of
               terriers, beagles, German shepherds, springer spaniels,   myocardium are present.
               Cavalier King Charles spaniels, and dachshunds are
               overrepresented. Cats with high‐degree second‐degree   Echocardiography
               and complete AV block are typically older than 10 years   An echocardiogram is indicated to identify concomi­
               of age. There is no evidence of breed or sex predisposi­  tant structural cardiac disease, which is frequent in
               tion in this species.                              cats  with  complete  AV  block. It is  also  essential  to
                                                                  identify cardiac neoplasia that can infiltrate and dis­
                                                                  rupt the AV nodal tissue, to assess systolic function in
               History and Clinical Signs                         the presence of myocarditis, and to determine the

               The hemodynamic effect of AV block depends on the   degree of volume overload secondary to chronic
               rate of ventricular contraction. However, one‐third of   bradycardia.
               cats, and occasionally dogs, with advanced AV block may
               show no apparent signs, and bradycardia is detected on   Other Methods
               physical  examination.  More  commonly,  animals  show   Serum cardiac troponin I can be used to assess the degree
               signs of anorexia, lethargy, exercise intolerance, disori­  of myocardial damage and raise a suspicion of myocardi­
               entation, episodic weakness, and syncopal episodes.   tis. Although a mild elevation of plasma cardiac troponin
               Some animals develop right‐sided congestive heart   I level is common in dogs with complete AV block,
                 failure and, less commonly, left‐sided congestive heart   marked increases suggest myocarditis as the cause for
               failure if the bradycardia is left untreated.      the AV block.
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