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49  Gastrointestinal Endoscopy  525

                                                                  mucosal defects are best assessed by collecting biopsies
  VetBooks.ir                                                     from the adjacent, more normal‐appearing mucosa
                                                                  rather than the center of the mass, as biopsies from this
                                                                  region are usually of poor diagnostic quality due to tissue
                                                                  necrosis, and the risk of perforation is increased
                                                                  substantially.


                                                                  Ileoscopy
                                                                  Indications
                                                                  Ileoscopy, while technically more challenging than many
                                                                  other gastrointestinal endoscopy procedures, is strongly
                                                                  recommended when endoscopic examination is being
                                                                  conducted as part of the approach to patients with gas-
                                                                  trointestinal disease, regardless of whether the primary
               Figure 49.16  Colonic view of the normal ileocolic junction in a   complaint is predominantly arising from upper or lower
               dog. The ileocolic sphincter, visible as a mushroom‐like protrusion   gastrointestinal tract signs. It is not unusual to document
               into the colonic lumen, occupies the lower half of the image.   substantial histological disagreement between duodenal
               Above the ileocolic sphincter, the entry to the cecum is visible,   and ileal mucosal biopsy specimens, with the ileal
               surrounded by a “ridge” of normal colonic mucosa. The anatomy of   mucosa often presenting with more severe changes. This
               this region, particularly the transition from colonic to cecal lumen,
               is highly variable in normal dogs.                 holds true with both dogs and cats.

                                                                  Patient Positioning and Preparation
                                                                  As ileoscopy requires a transcolonic approach, ideally
                                                                  the patient will be placed in left lateral recumbence. This
                                                                  is consistent with the positioning for upper gastrointesti-
                                                                  nal procedures. Ideally, the patient will receive preproc-
                                                                  edural preparation for colonoscopy. If there is no plan to
                                                                  fully assess the colonic mucosa and the sole reason for
                                                                  the procedure is to attempt to biopsy the ileal mucosa, a
                                                                  more abbreviated preparation protocol can be used,
                                                                  essentially several warm water enemas administered the
                                                                  evening before and once on the morning of the proce-
                                                                  dure (assuming a morning procedure time). This may
                                                                  provide sufficient space and visualization to allow tra-
                                                                  versal of the colon to the ileocolic junction, but there is a
                                                                  greater risk that the lower intensity preparation will
                                                                  result in inadequate visualization and failure of the
               Figure 49.17  A large, severely ulcerated mass lesion in the   procedure.
               descending colon of a canine patient. A marked increase in
               colonic mucosal granularity is also visible. Endoscopic biopsy of
               this lesion and the granular regions of colonic mucosa revealed   Equipment Choice
               lymphosarcoma.                                     Ileoscopy requires a flexible colonoscope with four‐way
                                                                  tip deflection, air/water insufflation and a large working
               Potential Abnormalities Observed during            channel, as used for colonoscopy procedures. Extra
               Colonoscopy Procedures                             length will be necessary to allow navigation into and
               After careful assessment of the mucosa for consistency   along the ileum, which may become limiting with larger
               in appearance, texture, the presence of masses or ero-  canine patients.
               sions and ulcerations as the endoscope is advanced,
               biopsy samples should be obtained from areas of interest   General Technique and Landmarks
               and several areas that are apparently normal as the endo-  The ileocolic junction is approached at the end of the
               scope is withdrawn. Mass lesions may also be biopsied   routine colonoscopy procedure, as described earlier. The
               but care must be taken to minimize the risk of colonic   endoscope tip is brought into contact with the center of
               wall perforation. Mass lesions or ulcerative lesions with   the ileocolic sphincter, similarly to the antral approach to
               severe mucosal distortions (Figure  49.17) or deep   the pylorus. As with the pyloric approach, excessive air
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