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action that interferes with protein
                                                                synthesis in susceptible organisms
                                             2. Contraindications and cautions
                                                             a. Contraindicated in clients with
                                                                hypersensitivity, myasthenia gravis,
                                                                parkinsonism, or eighth cranial nerve
                                                                damage
                                                             b. Used with caution in the older client, in
                                                                neonates because of renal insufficiency
                                                                and organ immaturity, and in young
                                                                infants because the medication may
                                                                cause CNS depression

                                                             c.        The risk of toxicity increases

                                                                when taken with other
                                                                aminoglycosides or nephrotoxicity- or
                                                                ototoxicity-producing medications.
                                             3. Side and adverse effects (Box 51-8)
                                             4. Interventions
                                                             a. Assess for hypersensitivity.
                                                             b. Monitor liver and renal function test
                                                                results.

                                                             c.        Monitor for ototoxic, neurotoxic,

                                                                and nephrotoxic reactions.
                                                             d. Perform baseline audiometric testing
                                                                and repeat every l to 2 months,
                                                                because the medication impairs the
                                                                eighth cranial nerve.

                                                             e.        Monitor for visual changes.

                                                             f. Assess hydration status and maintain
                                                                adequate hydration during therapy.
                                                             g. Monitor intake and output.
                                                             h. Assess urinalysis results.
                                                             i. Monitor for signs of peripheral neuritis.
                                             5. Client education: To notify the PHCP if hearing loss,
                                                changes in vision, or urinary problems occur
                    XVI. Influenza Medications
                                A. Vaccines
                                             1. Description
                                             2. Because the strain of influenza virus is different every
                                                year, annual vaccination is recommended (usually
                                                sometime during September to April); each time a flu
                                                vaccine is administered, the nurse should inform the
                                                client of any updated information regarding the
                                                vaccine.



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