Page 1640 - Saunders Comprehensive Review For NCLEX-RN

seizure disorder, depression, severe
anxiety, psychosis, or renal
insufficiency or in clients who use
alcohol
3. Side and adverse effects
a. Hypersensitivity
b. CNS reactions

c. Neurotoxicity

d. Seizures
e. Heart failure
f. Headache
g. Vertigo
h. Altered level of consciousness
i. Irritability, nervousness, anxiety
j. Confusion
k. Mood changes, depression, thoughts of
suicide
4. Interventions
a. Monitor level of consciousness.
b. Monitor for changes in mental status
and thought processes.
c. Monitor renal and hepatic function
tests.
d. Monitor serum medication level to
avoid the risk of neurotoxicity; the
peak concentration, measured 2 hours
after dosing, should be 25 to
35 mcg/mL (140 to 195 mcmol/L).

5. Client education

a. To take the medication after meals to
prevent gastrointestinal upset
b. To report signs of a rash or signs of
CNS toxicity
c. To avoid driving or performing tasks
that require alertness until the reaction
to the medication has been determined
d. About the need for monitoring serum
medication levels weekly, as
prescribed
H. Streptomycin
1. Description
a. An aminoglycoside antibiotic used with
at least 1 other antitubercular
medication
b. Bactericidal because of receptor-binding

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