Page 1635 - Saunders Comprehensive Review For NCLEX-RN

1. Description: Used only for pulmonary tuberculosis
2. Cautions: Can affect blood levels of some medications,
including oral contraceptives and warfarin, and some
medications used to treat HIV infection

3. Side and adverse effects

a. Red-orange–colored body secretions
b. Hepatotoxicity
4. Interventions
a. Obtain baseline liver function studies
and assess throughout therapy.

b. Observe for hepatotoxic effects;

if they occur, withhold the medication
and notify the PHCP.
5. Client education
a. That the medication can be taken
without regard to food
b. To avoid sunlight or ultraviolet light
until photosensitivity is determined
c. That red-orange–colored body
secretions may occur
C. Capreomycin sulfate
1. Description
a. Mechanism of action is unknown.
b. Used to treat MDR-TB when significant
resistance to other medications is
expected
c. Administered intramuscularly

2. Contraindications and cautions

a. The risk of nephrotoxicity, ototoxicity,
and neuromuscular blockade is
increased with the use of
aminoglycosides or loop diuretics.
b. Used with caution in clients with renal
insufficiency, acoustic nerve
impairment, hepatic disorder,
myasthenia gravis, or parkinsonism
c. Not administered to clients receiving
streptomycin

3. Side and adverse effects

a. Nephrotoxicity
b. Ototoxicity
c. Neuromuscular blockade
4. Interventions

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