Page 1638 - Saunders Comprehensive Review For NCLEX-RN

2. Contraindications and cautions
a. Contraindicated in clients with
hypersensitivity

b. Used with caution in clients

with diabetes mellitus or renal
dysfunction
3. Side and adverse effects
a. Anorexia, nausea, vomiting

b. Metallic taste in the mouth

c. Orthostatic hypotension

d. Jaundice

e. Mental changes

f. Peripheral neuritis

g. Rash
4. Interventions
a. Assess liver and renal function test
results.

b. Monitor glucose levels in the

client with diabetes mellitus.

c. Administer pyridoxine as

prescribed to reduce the risk of
neurotoxicity.
5. Client education
a. To take medication with food or meals
to minimize gastrointestinal irritation
b. To change positions slowly
c. To report signs of a rash, which can
progress to exfoliative dermatitis if the
medication is not discontinued
F. Aminosalicylic acid
1. Description
a. Inhibits folic acid metabolism in
mycobacteria
b. Used to treat MDR-TB when significant
resistance to other medications is
expected
2. Contraindications and cautions

a. Contraindicated with

hypersensitivity to aminosalicylates,

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