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a. Perform baseline audiometric testing.
b. Assess renal, hepatic, and
electrolyte levels before
administration.
c. Monitor intake and output.
d. Reconstituted medication may be
stored for 48 hours at room
temperature.
e. Administer intramuscularly, deep into a
large muscle mass.
f. Rotate injection sites.
g. Observe injection site for redness,
excessive bleeding, and inflammation.
5. Client education
a. Not to perform tasks that require
mental alertness
b. To report any hearing loss, balance
disturbances, respiratory difficulty,
weakness, or signs of hypersensitivity
reactions
D. Antibiotics
1. Description
a. Aminoglycoside antibiotics or
fluoroquinolones are given with at
least 1 other antitubercular medication.
b. Bactericidal because of receptor-binding
action interfering with protein
synthesis in susceptible
microorganisms
c. Gastrointestinal disturbances are the
most common side effect.
d. Fluoroquinolones are not
recommended for use in children.
2. Contraindications and cautions
a. Contraindicated in clients with
hypersensitivity, neuromuscular
disorders, or eighth cranial nerve
damage
b. Used with caution in the older client, in
neonates because of renal insufficiency
and immaturity, and in young infants
because it may cause CNS depression
c. The risk of toxicity increases if
taken with other aminoglycosides or
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