Page 1636 - Saunders Comprehensive Review For NCLEX-RN
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a. Perform baseline audiometric testing.

                                                             b.        Assess renal, hepatic, and

                                                                electrolyte levels before
                                                                administration.
                                                             c. Monitor intake and output.
                                                             d. Reconstituted medication may be
                                                                stored for 48 hours at room
                                                                temperature.
                                                             e. Administer intramuscularly, deep into a
                                                                large muscle mass.
                                                             f. Rotate injection sites.
                                                             g. Observe injection site for redness,
                                                                excessive bleeding, and inflammation.

                                             5.        Client education

                                                             a. Not to perform tasks that require
                                                                mental alertness
                                                             b. To report any hearing loss, balance
                                                                disturbances, respiratory difficulty,
                                                                weakness, or signs of hypersensitivity
                                                                reactions
                                D. Antibiotics
                                             1. Description
                                                             a. Aminoglycoside antibiotics or
                                                                fluoroquinolones are given with at
                                                                least 1 other antitubercular medication.
                                                             b. Bactericidal because of receptor-binding
                                                                action interfering with protein
                                                                synthesis in susceptible
                                                                microorganisms
                                                             c. Gastrointestinal disturbances are the
                                                                most common side effect.
                                                             d. Fluoroquinolones are not
                                                                recommended for use in children.
                                             2. Contraindications and cautions
                                                             a. Contraindicated in clients with
                                                                hypersensitivity, neuromuscular
                                                                disorders, or eighth cranial nerve
                                                                damage
                                                             b. Used with caution in the older client, in
                                                                neonates because of renal insufficiency
                                                                and immaturity, and in young infants
                                                                because it may cause CNS depression

                                                             c.        The risk of toxicity increases if

                                                                taken with other aminoglycosides or



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