Page 2217 - Saunders Comprehensive Review For NCLEX-RN
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neurological symptoms including headache, dizziness, vertigo, ataxia, depression,
               and seizures. Options 1, 2, and 6 are unrelated to these medications.
                  Test-Taking Strategy: Focus on the subject, adverse effects of sulfonamides. It is
               necessary to know the adverse effects associated with these medications to answer
               correctly. Remember that nephrotoxicity, bone marrow suppression, and GI
               symptoms are adverse effects of sulfonamides.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Immune Medications: Sulfonamides
                  Health Problem: Adult Health: Immune: Infections
                  Priority Concepts: Clinical Judgment; Immunity
                  Reference: Burchum, Rosenthal (2016), pp. 1063-1064.


                   782. Answer: 3


                  Rationale: Didanosine can cause pancreatitis. A serum amylase level that is
               increased to 1.5 to 2 times normal may signify pancreatitis in the client with acquired
               immunodeficiency syndrome and is potentially fatal. The medication may have to be
               discontinued. The medication is also hepatotoxic and can result in liver failure.
                  Test-Taking Strategy: Focus on the subject, adverse effects of didanosine.
               Recalling that this medication can cause damage to the pancreas and is hepatotoxic
               will direct you to the correct option.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Immune Medications: Antivirals
                  Health Problem: Adult Health: Immune: Immunodeficiency Syndrome
                  Priority Concepts: Clinical Judgment; Safety
                  Reference: Skidmore-Roth (2017), pp. 362-364.


                   783. Answer: 3


                  Rationale: Hypertension can occur in a client taking cyclosporine, and because
               this client is also complaining of a headache, the blood pressure is the vital sign to be
               monitored most closely. Other adverse effects include infection, nephrotoxicity, and
               hirsutism. Options 1, 2, and 4 are unrelated to the use of this medication.
                  Test-Taking Strategy: Note the strategic words, most likely. Focus on the name of
               the medication and recall that this medication can cause hypertension. Also, noting
               that the client has a headache will assist you in answering correctly.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Immune Medications: Immunosuppressants
                  Health Problem: Adult Health: Immune: Transplantation
                  Priority Concepts: Clinical Judgment; Immunity
                  Reference: Lewis et al. (2017), pp. 209, 211.



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