Page 2218 - Saunders Comprehensive Review For NCLEX-RN
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784. Answer: 3


                  Rationale: Amikacin is an aminoglycoside. Adverse effects of aminoglycosides
               include ototoxicity (hearing problems), confusion, disorientation, gastrointestinal
               irritation, palpitations, blood pressure changes, nephrotoxicity, and hypersensitivity.
               The nurse instructs the client to report hearing loss to the PHCP immediately.
               Lethargy and muscle aches are not associated with the use of this medication. It is
               not necessary to contact the PHCP immediately if nausea occurs. If nausea persists
               or results in vomiting, the PHCP should be notified.
                  Test-Taking Strategy: Note the strategic word, immediately. Recalling that this
               medication is an aminoglycoside (most aminoglycoside medication names end in -
               cin) and that aminoglycosides are ototoxic will direct you to the correct option.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Immune Medications: Aminoglycosides
                  Health Problem: Adult Health: Immune: Infections
                  Priority Concepts: Client Education; Safety
                  Reference: Burchum, Rosenthal (2016), pp. 1052-1053.


                   785. Answer: 4


                  Rationale: Foscarnet is toxic to the kidneys. The serum creatinine level is
               monitored before therapy, two or three times per week during induction therapy,
               and at least weekly during maintenance therapy. Foscarnet also may cause
               decreased levels of calcium, magnesium, phosphorus, and potassium. Thus, these
               levels also are measured with the same frequency.
                  Test-Taking Strategy: Focus on the subject, the laboratory value to be monitored.
               Recalling that this medication is nephrotoxic will direct you to the correct option.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Immune Medications: Antivirals
                  Health Problem: Adult Health: Immune: Immunodeficiency Syndrome
                  Priority Concepts: Clinical Judgment; Safety
                  Reference: Hodgson, Kizior (2018), pp. 501-502.


                   786. Answer: 1


                  Rationale: Stavudine is an antiretroviral used to manage human
               immunodeficiency virus infection in clients who do not respond to or who cannot
               tolerate conventional therapy. The medication can cause peripheral neuropathy, and
               the nurse should monitor the client’s gait closely and ask the client about
               paresthesia. Options 2, 3, and 4 are unrelated to this medication.
                  Test-Taking Strategy: Note the strategic word, most. Focus on the name of the
               medication. Recalling that this medication causes peripheral neuropathy will direct
               you to the correct option.



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