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Difference in Risk Factors between Small Vessel Disease and Large

Vessel Subtype of Ischemic Stroke

Sucharinee Srisawat RN., Nipaporn Chaiyachet RN., Rattana Janjeam MD.,

Suparus Wangtongkum MD.

Chiangmai Neurological Hospital, Department of Medical Services,

Ministry of Public Health ,Chiangmai Province ,Thailand

Background: Stroke, a disease of the cerebral blood vessels, is known as

paralysis disease in Thailand and is a major public health problem. Stroke is a

chronic disease with a lengthy development, leading to a paralytic state in

which the patient faces obstacles doing his/her daily routine and needs to

depend upon others. The cause of ischemic stroke are hypertension, diabetic,

hyper cholesterol, atrial fribilation, carotid stenosis alcohol and smoking.

However, the risk factors of small vessel disease (SVD) and large vessel disease

(LVD) might be different.

Objective: To determine the difference of risk of Small Vessel Disease and

Large Vessel Disease.

Method: The retrospective review of the prospective stroke database of the

acute ischemic stroke patient who received treatment in Chiangmai

Neurological Hospital between Jan 2009 to Dec 2013 was performed. TOAST

classification was applied to classify stroke subtypes. SVD and LVD was

included in the study. Demographic data and risk factors were analyzed.

Result: A total of 1,092 ischemic stroke patients were joined but 20 clients

were excluded. SVD group was 579 and LVD group was 493 patients. Advance

in age, myocardial Infarction, atrial fibrillation and female sex were dominant in

th
19 Annual Academic Meeting of Prasat Neurological Institute, 2015