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2wU ATP m„wó nq| weRvwiZ ‡Kv-GbRvBg †_‡K nvB‡Wªv‡Rb Avqb (2H ) FAD Gi gva¨‡g Ges BjKUªb mvB‡Uv‡µvg¸‡jvi gva¨‡g cÖevwnZ n‡q
†k‡l 1/2 O2 Gi mv‡_ wgwjZ nq Ges cvwb ˆZwi K‡i| Kv‡RB B‡jKUªb cÖevnZ‡š¿i B‡jKUª‡bi †kl MÖnxZv n‡”Q Aw·‡Rb|
GKbR‡i mevZ k¦m‡bi wbU Drcv`b
k¦m‡bi ch©vq Drcvw`Z e¯Íy e¨wqZ e¯Íy bxU Drcv`b
2 AYy cvBiæwfK A¨vwmW
MøvB‡KvjvBwmm 2 AYy NADH2 4 ATP
4 AYy ATP 2 AYy ATP 2 ATP
2 AYy A¨vwmUvBj †Kv-G 2 AYy CO2
2 AYy CO2
A¨vwmUvBj †Kv-G m„wó 2 AYy cvBiæwfK A¨vwmW
2 AYy NADH2 6 ATP
4 AYy CO2 4 AYy CO2
6 AYy NADH2 18 ATP
‡µem Pµ 2 AYy FADH2 2 AYy A¨vwmUvBj †Kv-G 4 ATP
2 AYy GTP 2 ATP
AevZ k¦mb t †h k¦mb cÖwµqvq Rxe‡Kv‡li k¦mwbK e¯‘ (cÖavYZ Møy‡KvR) Aw·‡R‡bi Abycw¶wZ‡Z Am¤ú~Y©iæ‡c Rvwin n‡q B_vBj A¨vj‡Kvnj,
Kve©b WvB A·vBW I Aí cwigvY kw³ wbM©Z nq Zv‡K AevZ k¦mb e‡j| mvaviYZ †cÖvK¨vwiqU (e¨vK‡Uwiqv) Rx‡e AevZ k¦mb †`Lv hvq|
C6H12O6 → 2C2H5OH + 2CO2+ 20 Kcal kw³
AevZ k¦mb‡K `ywU ch©v‡q fvM Kiv hvq, h_v -
1. MøvB‡KvjvBwmm t GwU mevZ k¦mb cÖwµqvi Abyiæc|
2. cvBiæwfK A¨vwm‡Wi Am¤ú~Y© RviY t †Kv‡l Aw·‡Rb Abycw¯’Z _vK‡j cvBiæwfK A¨vwmW Am¤ú~Y©fv‡e RvwiZ n‡q B_vBj
A¨vj‡Kvnj ev j¨vKwUK A¨vwmW m„wó K‡i| †hgb-
K) B_vBj A¨vj‡Kvnj m„wó t G cÖwµqv `ywU av‡c m¤úbœ nq| cÖ_gZ cvBiæwfK Kv‡e©vw·‡jR GbRvB‡gi wµqvq cvBiæwfK A¨vwmW
Kv‡e©vw·‡jkb c×wZ‡Z CO2 wegy³ K‡i A¨vwmUvjwWnvB‡W cwiYZ nq| wØZwqZ wWnvB‡WªvwR‡bR GbRvB‡gi wµqvq
A¨vwmUvjwWnvBW NADH2 Øviv weRvwiZ n‡q B_vBj A¨vj‡Kvnj Drcbœ K‡i|
cvBiæwfK Kv‡e©vw·‡jR
I. CH3-CO-COOH ------------------------- → CH3-CHO + CO2
cvBiæwfK A¨vwmW A¨vwmUvjwWnvBW
wWnvB‡WªvwR‡bR
II. CH3-CHO + NADH2 ------------------------- → CH3- CH2 -CHO + NAD
A¨vwmUvjwWnvBW B_vBj A¨vj‡Kvnj
L) j¨vKwUK A¨vwmW m„wó t †Kv‡l Aw·‡R‡bi Abycw¯’wZ‡Z wWnvB‡WªvwR‡bR GbRvB‡gi wµqvq cvBiæwfK A¨vwmW NADH2 Øviv
weRvwiZ n‡q j¨vKwUK A¨vwmW cÖ¯‘Z K‡i| AevqyRxex QvovI D”P‡kªYxi cÖvYxi †ckx‡Z j¨vKwUK A¨vwmW m„wó nq| D”P‡kªYxi
Dw™¢‡` †Kvb j¨vKwUK A¨vwmW m„wó nq bv|
wWnvB‡WªvwR‡bR
CH3-CO-COOH + NADH2 -------------------------→ CH3- CHOH-COOH + NAD
cvBiæwfK A¨vwmW j¨vKwUK A¨vwmW
dvi‡gb‡Ukb ev MuvRb t ‡Kv‡li evB‡i Aw·‡R‡bi Abycw¯’wZ‡Z RvB‡gR GbRvB‡gi cÖfv‡e& †n‡·vR Kv‡e©vnvB‡WªU AYy Am¤ú~Y©fv‡e RvwiZ n‡q
B_vbj ev j¨vKwUK A¨vwmW m„wói cÖwµqv‡K dvi‡gb‡Ukb ev MuvRb e‡j| KwZcq e¨vK‡Uwiqv I GK‡Kvlx C‡÷ dvi‡gb‡Ukb N‡U| divmx
imvqbwe` jyB cv¯‘i (1865) C‡÷i dvi‡gb‡Ukb cÖwµqvi weeiY †`b Ges dvi‡gb‡Ukb‡K Aw·‡Rbwenxb k¦mb wn‡m‡e A¨vL¨vwqZ K‡ib|
wk퇶‡Î dvi‡gb‡Ukb / AevZ k¦m‡bi e¨envi t
1. g` wk‡í t C÷ e¨envi K‡i Av½yi, Av‡cj, bvmcvwZ, Zv‡ji im, wPUv¸o BZ¨vw` †_‡K dvi‡gb‡Ukb cÖwµqvq g` Drcv`b Kiv nq| G
cÖwµqvq Av½y‡ii im †_‡K BqvBb Ges Av‡c‡ji im †_‡K wmWvi ˆZwi Kiv nq|
2. A¨vj‡Kvnj wk‡í t Pvj, AvUv, evwj©, wPUv¸o I Ab¨vb¨ Kv‡e©vnvB‡WªU RvZxq `ªe¨ †_‡K dvi‡g‡›Ukb cÖwµqvq B_vbj cÖ¯‘Z Kiv nh|
3. cvDiæwU wk‡í t †ewKs C÷‡K gq`vi mv‡_ wgwk‡q wbw`©ó ZvcgvÎvq †i‡L w`‡j wbw`©ó mgq c‡i dvi‡gb‡Ukb cÖwµqvq A¨vj‡Kvnj I
CO2 Drcbœ nq| CO2 gq`vi `jvi g‡a¨ ey`ey` m„wó K‡i d‡j gq`vi `jv dy‡j D‡V| G Ae¯’vq gq`v‡K Pzjøxi Zv‡c Mig Kiv n‡j
CO2 Gi ey`ey`¸‡jv cÖmvwiZ n‡q †d‡U hvq Ges gq`v¸‡jv ¯úwÄ cvDiæwU‡Z cwiYZ nq| Gmgq A¨vj‡Kvnj ev®úvKv‡i †ei n‡q hvq|
4. `y» wk‡í t `y‡ai mv‡_ Lactobacillus I Streptococcus MYfy³ wewfbœ cÖRvwZi e¨vK‡Uwiqv wgwk‡q dvi‡gb‡Ukb cÖwµqvq `B,
cwbi, gvLb BZ¨vw` Drcv`b Kiv nq|
5. Pv wk‡í t Pv cÖwµqvRvZKi‡Yi mgq ¸Uv‡bv Pv cvZv‡K 30 C ZvcgvÎvq N‡ii †g‡S‡Z 3-4 †mw›UwgUvi cyiæ K‡i 3-5 N›Uv wewQ‡q †i‡L
0
dvi‡gb‡Ukb NUv‡bv nq, d‡j cvZv¸‡jv Zvgª eY© aviY K‡i I myMÜhy³ nq|
6. Ilya wk‡í t AvaywbK RxecÖhyw³‡Z e¨vK‡Uwiqvi dvi‡g‡›Ukb Øviv wewfbœ GbRvBg, mvBwUªK A¨vwmW, Bbmywjb, wUKvmn bvbvb g~j¨evb Ilya
ˆZwi Kiv nq|
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