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Chapter 30  Pregnancy and neonatal haematology   /  417




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                                                                  Kleihauer positive  Fetomaternal bleed






                                                         DAT negative*  Check Kleihauer  MCV low  α-Thalassaemia




                                                Raised reticulocytes  Check DAT  Kleihauer negative  Check MCV  The investigation of neonatal anaemia.  G6PD, glucose 6 phosphate dehydrogenase; MCV, mean corpuscular volume.    The   -   -








                                   Anaemia  Reticulocyte count  DAT positive  Probable HDN  Pyruvate kinase deficiency direct antiglobulin test (DAT) test may be negative in haemolytic disease of the newborn (HDN) caused by ABO incompatibility.





                                                Low reticulocytes              MCV normal or high  Membrane disorder  G6PD deficiency







                                                       Red cell aplasia  Parvovirus B19  Diamond–Blackfan Alloimmune anti-Kell





                                                                                            Figure 30.4
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