Page 1226 - Basic _ Clinical Pharmacology ( PDFDrive )

1212 Index

Fluke infections Folacin, 606t. See also Folic acid diuresis using, 262f, 262t, 262–264,
niclosamide for, 943 Folate antagonists, 834–837. See also 273t
praziquantel for, 944–945 specific types heart failure treated with, 221, 224
Flumazenil, 387, 390, 392, 393t. See also DNA gyrase inhibitors, 837–840, 840t Fusion proteins, 93, 94f. See also specific
Benzodiazepine antagonists preparations available, 840t types
Flunarizine, 291 sulfonamides, 834–836, 840t
Flunisolide, 355, 362t. See also Folate deficiency, 594t, 599, 600 G
Corticosteroids, inhaled (aerosol); Folate synthesis inhibitors, 926 GABA, 378. See Gamma (γ)-aminobutyric
Corticosteroids, synthetic fansidar, 926 acid (GABA)
Fluocinonide, 1080t proguanil, 919f, 926 GABA A receptor, 386, 387f
Fluoride, 781 pyrimethamine, 919f, 926 GABAergic synapse, inhibitory, 412f
Fluoropyrimidines sulfadoxine, 919f, 926 Gabapentin
capecitabine, 958t, 959 sulfadoxine-pyrimethamine, 920t analgesia using, 560b
5-fluorouracil, 958t, 959 Folic acid, 598–600, 599b, 599f, 606t restless legs syndrome treated with, 507
Fluoroquinolones, 837–840, 840t chemistry of, 599, 599f seizures treated with, 420, 433t, 436t
adverse effects of, 839–840 clinical pharmacology of, 600 spasmolytic actions of, 487
antibacterial activity of, 837–839, 838f, in hematopoiesis, 591 tremor treated with, 503
838t pharmacodynamics of, 597f, 600 GABA receptor agonists, 387
chemistry of, 836, 838f pharmacokinetics of, 597f, 599–600 GABA receptor antagonists, 387
clinical uses of, 839 preparations available, 607t GABA receptor inverse agonists, 387
mechanism of action of, 837 public health dilemma of, 599b GABA receptors
pharmacokinetics of, 838t, 839 Folic acid deficiency, 599, 600, 606t chloride channel versatility of, 386, 387f,
preparations available, 840t Follicles, 721 388b
resistance of, 839 Follicle-simulating hormone (FSH), 668f, in CNS, 373, 378
tuberculosis treated with, 848 668–669, 669t heterogeneity and pharmacologic
5-Fluorouracil (5-FU), 958t, 959 chemistry and pharmacokinetics of, 674 selectivity of, 387b
actinic keratoses treated with, 1083 in ovarian function, 720 in Huntington’s disease, 503
dihydropyrimidine dehydrogenase on, pharmacodynamics of, 674 Galanin, 92t
78, 78t, 81 on testis, 740 Galantamine, 1063
Fluoxetine Follitropin alfa, 674, 683t Gallium nitrate, 783
blocking effects of, 542t Follitropin beta, 674, 683t Gallstones, bile acid therapy for,
depression treated with, 532, 549t, 552 Fomepizole, 405, 406t 1113–1114, 1116t, 1117t
dosing of, 546t Fondaparinux, 612–616. See also Heparin Gametocides, malaria, 917
pharmacokinetics of, 540t Food & Drug Administration (FDA) Gamma (γ)-aminobutyric acid (GABA)
poisoning with, 1042 description of, 15, 16t in brain, 373
serotonergic action of, 291 on prescribing, 1151 in CNS, 376t, 378
Fluoxymesterone, 740–743, 741t. See also Food poisoning, 1034 functions of, 92t
Androgens and anabolic steroids Forced diuresis, for poisoning, 1040 neuropharmacology of, 386–387
Fluphenazine Formaldehyde, 900 Gamma-delta T (γδT), 978
Huntington’s disease treated with, 505, Formalin, 900 Gamma (γ)-hydroxybutyric acid (GHB),
508t Formoterol, 351, 362t 577t, 582, 583f
psychosis treated with, 511–524, 513f, Fosamprenavir, 872t, 880 Ganaxolone, 435
520t, 528t. See also Antipsychotic Fosaprepitant, 314, 317t, 1105. See also Ganciclovir, 868, 868t
agents Substance P, antagonists of Ganglion blockers. See also specific types
Fluprednisolone, 709t. See also Corticoste- Foscarnet, 868t, 869 on cardiovascular response to
roids, synthetic Fosfomycin, 810–811 phenylephrine, 145, 147f
Flurazepam. See also Benzodiazepines Fosinopril, 187 chemistry and pharmacokinetics of, 133,
description of, 382f, 393t Fosphenytoin, 418, 435t 134f
pharmacokinetics of, 385t Fospropofol, 452–453 clinical applications of, 134, 135t
Flurbiprofen, 644f, 645t, 647. See also Fowler’s solution, 1025 hypertension treated with, 181, 193t
Nonsteroidal anti-inflammatory Fresh-frozen plasma, 616 pharmacodynamics of, 134
drugs (NSAIDs) Frovatriptan, 291t, 296t pharmacology of, 133–134
Flutamide, 744, 744f, 972 Full agonists, 5, 6f preparations available, 136t
Fluticasone, 355, 362t. See also Corticoste- Fulvestrant, 739 toxicity of, 134, 135t
roids, inhaled (aerosol) Fumaric acid esters, 1079 Ganirelix, 678–679, 683t
Fluvastatin, 632–634, 639t Fungal meningitis, iatrogenic, 859b Gantacurium, 477. See also Neuromuscular
Fluvoxamine, 546t, 550t Furanocoumarins, 72 blocking drugs
Focal seizures, 410, 433 Furosemide, 224t. See also Diuretics Garlic (Allium sativum), 1135–1136, 1145