Page 1224 - Basic _ Clinical Pharmacology ( PDFDrive )
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1210     Index


                 Epinephrine reversal, 157         Erythema nodosum leprosum, 850     Estrogen and progesterone inhibitors and
                 Epinephrine therapy               Erythromycin                               antagonists, 737–740
                   anaphylaxis treated with, 152–153  acne treated with, 1071           anastrozole, 739
                   asthma treated with, 350, 362t    description of, 819–820, 824t      danazol, 738–739
                   cardiac arrest treated with, 152  prokinetic activity of, 1098       fadrozole, 739
                 Epirubicin, 965                   Erythropoietin (rHuEPO, EPO), 601–602,   fulvestrant, 739
                 Epithelial Na channel (ENaC), 258, 258f   602t, 606t, 997t             GnRH and analogs, 739
                 Eplerenone, 191t, 224t, 717. See also   Escalation, dose, 952          letrozole, 739
                        Aldosterone antagonists; Diuretics  Escitalopram, 540t, 542t, 546t, 549t.   mifepristone, 738
                   diuresis using, 265–267, 266t, 273t     See also Selective serotonin   tamoxifen and related partial agonist
                   drug interactions of, 1170t–1171t       reuptake inhibitors (SSRIs)        estrogens, 737f, 737–738
                   heart failure treated with, 220  Eslicarbazepine (acetate), 417, 433t  Estrogen receptors, 707f, 724
                 Epoetin alfa, 601–602, 602t, 606t  Esmolol, 164t, 167. See also b-receptor   Estrogen response elements (EREs), 724
                 Epoprostenol (PGI 2  analog), 324f        antagonist drugs           Estrone. See also Estrogen(s)
                  pulmonary hypertension treated with, 335  arrhythmias treated with, 239t–240t,   natural, 704f, 722, 723f
                  structure of, 333f                       243, 251t                    synthetic, 723, 723f
                 Epothilone-D, 1063                  hypertension treated with, 183   Eszopiclone, 382, 383f, 385t, 391, 394t.
                 Epoxide hydrolases (EHs), 63, 64t  Esomeprazole, 1091–1095. See also proton-  See also Hypnotics
                 Epoxyeicosatrienoic acid (EET), 325, 332  pump inhibitors (PPIs)     Etanercept
                 e-prescribing, 1150–1151          Esotropia, accommodative, 118        description of, 993
                 Eprosartan                        Essential tremor, 503                psoriasis treated with, 1079
                  hypertension treated with, 189   Estazolam, 393t. See also Benzodiazepines  rheumatic disorders treated with, 654f, 655
                  on vasoactive peptides, 317t     Esters, 61t                        Ethacrynic acid, for diuresis, 262f, 262t,
                 Eptifibatide, 621                 Estradiol. See also Estrogen(s)            262–264, 273t
                 Equilenin, 723                      natural, 704f, 722, 723f         Ethambutol, 842, 843t, 845–846, 851t
                 Equilibrium potential, 229          synthetic, 723, 723f             Ethanol, 382, 396–404, 406t. See also
                 Equilin, 723                      Estriol                                    Sedative-hypnotic drugs
                 Erectile dysfunction                natural, 704f, 722, 723f           alcohol use disorder, 396
                  alpha-receptor antagonists for, 162  synthetic, 723, 723f. See also Estrogen(s)  drugs for, 406t, 407t
                  drugs for, 200b, 211t            Estrogen(s), 722–727. See also specific types  antisepsis and disinfection uses of, 898,
                 Erection, penile, 344               adverse effects of, 726–727              898t
                 Erethism, 1028                      on bone homeostasis, 779           clinical pharmacology of, 402–404
                 Ergocalciferol, 789t. See also Vitamin D  clinical uses of               acute alcohol intoxication, 402–403
                 Ergoline, 292                         hypogonadism, primary, 725         alcoholism, 404, 406t, 407t
                 Ergonovine, 294–295, 297t. See also Ergot   ovulation suppression, 726   alcohol withdrawal syndrome, 403,
                        alkaloids                      postmenopausal hormonal therapy,       403f, 406t, 407t, 585, 589t
                 Ergosterol, 854                           725–726                      dependence on, 396, 400
                 Ergot alkaloids, 292–296, 297t–298t  contraindications to, 727         drug interactions, 402, 1157t
                  accidental ingestion of, 292       drug interactions of, 1166t        in OTC agents, 1129t
                  applications of                    natural, 722f, 722–723             pharmacodynamics of, 398–402
                    hyperprolactinemia, 295          pharmacokinetics of, 723–724         in acute consumption, 398t, 398–399
                    migraine, 295                    physiologic effects of, 724–725      alcohol-drug interactions in, 402
                    postpartum hemorrhage, 295         blood coagulation, 725             animal research on, 399b
                    senile cerebral insufficiency, 295  edema, 725                        chronic consumption, 399–402
                    variant angina diagnosis, 295      endometrial, 724                     cancer risk, 402
                  chemistry and pharmacokinetics of,   female maturation, 724               cardiovascular system, 401
                        292–293, 293t                  mechanism of action in, 707f, 724    endocrine system and electrolyte
                  origins of, 292                      metabolic and cardiovascular,          balance, 401
                  pharmacodynamics of, 293t, 293–295,      724–725                          fetal alcohol syndrome, 401
                        294f                           progesterone receptor synthesis,     immune system, 402
                  preparations available, 297t–298t        725                              liver and GI tract effects, 399–400
                 Ergotamine, 160, 294–295, 297t        stress system, 725                   nervous system, 400–401
                 Ergotism, 292, 292b                   sympathetic nervous system, 725  poisoning with, 396, 408, 1045
                 Ergotropic nervous system, 100      preparations and dosages of, 724t, 727,   prevalence of use, 396
                 Eribulin, 963–964                         745t                         tolerance and dependence on, 396, 400
                 Erlotinib, 966t, 968                synthetic, 723, 723f               withdrawal syndrome management for, 403
                 Errors, prescribing, 1148–1149      types of, 722–723                    drugs in, 406t, 407t, 585, 589t
                 Ertapenem, 803t, 807, 812t        Estrogen agonists, 737f, 737–738       time course of, 403f
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