Page 1250 - Basic _ Clinical Pharmacology ( PDFDrive )

1236 Index

Preload, 215f, 216 Profile, pharmacologic, 12 hypertension treated with, 179t,
Premature depolarizations, 218 Progabide, 487 182–183, 191t
Premenstrual dysphoric disorder, 533 Progesterone, 721f, 727–731 hyperthyroidism treated with, 696, 699,
Prescribing, rational, 1148–1149 adverse effects of, 731 700, 701t
Prescribing authority, 1152t clinical uses of, 731 migraine headache prophylaxis uses of,
Prescriptions, 1147f, 1148–1155 contraindications and cautions with, 731 168, 291
abbreviations in, 1149t diagnostic uses of, 731 physiologic effects of, 38
compliance in, 1150–1151 pharmacokinetics of, 728 structure of, 163f
conversions for, 1148 physiologic effects of, 729–731 tremor treated with, 503
elements of, 1147f, 1147–1148 Progesterone receptor synthesis, estrogens Propylene glycol
e-prescribing in, 1150, 1151 in, 725 as dermatologic vehicle, 1082
errors in, 1148–1149 Progestin-only contraception, 736 keratolytic actions of, 1082
errors of omission in, 1149–1150 Progestins, 727–731 Propylthiouracil (PTU)
inappropriate drug prescriptions in, adverse effects of, 731 description of, 693–695, 694f, 701t
1150 clinical uses of, 731 thyrotoxicosis in pregnancy treated with,
legal factors in, 1151–1154 contraindications and cautions with, 731 700
controlled substances, 1153, 1153t diagnostic uses of, 731 Prorenin, 301
drug safety surveillance, 1153–1154 natural (progesterone), 721f, 727–728 Prorenin receptors, 305
FDA, 1151 pharmacokinetics of, 728 Prostacyclin (PGI 2 ), 323
labeled and off-labeled uses, 1153 physiologic effects of, 729–731 Prostaglandin(s)
right to prescribe, 1151, 1152b synthetic, 728, 728t, 729, 729f, effects of, 327–331
poor writing of, 1150 730t–731t on kidney, 259
rational prescribing in, 1148–1149 Proguanil, 919f, 926 structures of, 333f
security of, 1151 Proinsulin, 747 Prostaglandin analogs
socioeconomic factors in Proinsulin C, 748f gastric mucosa protection using, 1096
generic prescribing, 1154–1155 Projection neurons, 373, 373f structures of, 333f
other cost factors, 1155 Prokinetic agents, 1096–1098, 1115t Prostaglandin endoperoxide synthase
Preservatives, 901 cholinomimetic agents, 1097 products, 323, 324f
Presynaptic regulation, autonomic, 100, macrolides, 1098 Prostaglandin F 2α (PGF 2α ), 333f
102t, 103 mechanism of action of, 1096–1097, 1097f Prostanoid biosynthesis, 323, 324f
Prevertebral ganglia, 91 metoclopramide and domperidone, Prostanoid mediators, from arachidonic
Prilocaine, 462, 471, 472t. See also 1097–1098 acid, 646f
Anesthetics, local preparations available, 1117t Prostanoid receptors, 326–327, 327f, 328t
Primaquine, 919f, 920t, 925–926 Prolactin antagonist, 679. See Dopamine Prostate cancer
Primary amine, 9, 60t agonists androgen suppression for, 743, 745t
Primary chemotherapy, 949 Prolactin (PRL), 668, 668f, 669t, 679 chemotherapy for, 972
Primary generalized glucocorticoid Proliferation signal inhibitors, 986–987 degarelix and abarelix for, 679
resistance, 710 Promethazine, 283t, 383, 1105–1106 gonadotropin-releasing hormone agonists
Primidone Pro-opiomelanocortin, 703 for, 677–678
seizures treated with, 424–425, 425f, Propafenone, 239t, 240t, 242–243, 251t Prostatectomy, 124, 136
433t, 436t Propantheline, 126f Protamine sulfate, 614
tremor treated with, 503 Prophylaxis, antimicrobial Protease inhibitors (PIs)
Principal cells, 258, 258f nonsurgical, 914, 915t, 916 atazanavir, 871t, 879–880
Principles, pharmacology, 3–10 NRC wound classification criteria and, darunavir, 871t, 880
drug–body interactions in, 5–10 914b fosamprenavir, 872t, 880
drug groups in, 10 surgical, 913–914, 914t fundamentals of, 879
nature of drugs in, 3–5 Propiverine, 131. See also Muscarinic hepatitis C treated with, 889–891, 890f
Prinzmetal angina, 194 receptor blockers human immunodeficiency virus treated
Private pharmacy benefits manager, 1154 Propofol, for anesthesia, 450f, 450t, with, 879–882
Probenecid, 660f, 661, 1171t 450–452 indinavir, 872t, 880–881
Procainamide, 237–239, 239t, 240t, 250t Propoxyphene, 568. See also Opioid lopinavir, 872t, 881
Procaine, 460f, 461b, 472t agonists nelfinavir, 872t, 881
Procaine penicillin G, 799. See also Propranolol, 24, 164t, 165, 170t. See also in pregnancy, 879t
Penicillin(s) b-receptor antagonist drugs ritonavir, 872t, 881
Procarbazine, 955t, 956 angina pectoris treated with, 210t saquinavir, 872t, 881–882
Prochlorperazine, 1105–1106 arrhythmia treated with, 239t–240t, simeprevir, 890–891
Procyclidine, 501t, 508t 243, 251t sofosbuvir, 889
Prodrug, 7 case study on, 20, 40 tipranavir, 873t, 882