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15 Enzymes581K. WILSON15.1 Characteristics and nomenclature 58115.2 Enzyme steady-state kinetics 58415.3 Analytical methods for the study of enzyme reactions 60215.4 Enzyme active sites and catalytic mechanisms 61115.5 Control of enzyme activity 61515.6 Suggestions for further reading 62416 Principles of clinical biochemistry625J. FYFFE AND K. WILSON16.1 Principles of clinical biochemical analysis 62516.2 Clinical measurements and quality control 62916.3 Examples of biochemical aids to clinical diagnosis 64016.4 Suggestions for further reading 65816.5 Acknowledgements 65917 Cell membrane receptors and cell signalling660K. WILSON17.1 Receptors for cell signalling 66017.2 Quantitative aspects of receptor%u2013ligand binding 66317.3 Ligand-binding and cell-signalling studies 68017.4 Mechanisms of signal transduction 68517.5 Receptor trafficking 70317.6 Suggestions for further reading 70718 Drug discovery and development709K. WILSON18.1 Human disease and drug therapy 70918.2 Drug discovery 71818.3 Drug development 72718.4 Suggestions for further reading 734Index736The colour figure section is between pages 128 and 129ix Contents