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Clinical pharmacy 2024/2025 Level 3 Pharm D Pharmacology 1 (PO 502)

Antihypertensive Drugs

Classification of antihypertensive agents

1. Diuretics

I. α blockers Prazosin, terazosin, phentolamine
2. Adrenergic receptor
II. β blockers Propranolol, metoprolol, atenolol
antagonists:
III. α & β blockers Carvedilol, Labetalol.

3. Angiotensin converting
Captopril, enalapril.
enzyme (ACE) inhibitors

4. Angiotensin II receptor
Losartan, irbesartan.
antagonist

5. Renin antagonist Aliskiren, Remikiren

6. Calcium channel blockers Verapamil, diltiazem, nifedipine.

7. α-adrenergic blocking
Prazosin, doxazosin, and terazosin
agents

8. Centrally acting
Clonidine, methyldopa.
sympathetic inhibitors:

9. Adrenergic neurons
Reserpine, guanethidine
blocking agents

10. Direct vasodilators Hydralazine and minoxidil

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