Page 149 - Phytochemistry 2 (06-PG 605)
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3-(+)-Discodermolide
It is a cytotoxic polyketide natural marine product, that was
isolated in 1990, from deep-water Caribbean sponge,
Discodermia dissolute.
The natural source of disocdermolide does not provide
sufficient material for advanced evaluation, with the reported
isolated yield of 7 mg from 434 g of frozen spongeThe only
reliable source of discodermolide is total chemicalsynthesis.
