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02/04/2024

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                 (pathophysiology)
             According to mechanism

     • Osmotic
     • Secretory
     • Exudative
     • motor

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     Osmotic diarrhea:

     Occurs when a nonabosrbable solute pulls excess water into the
                                      intestinal tract

     • Ingestion of large meals or certain osmotic substances (e.g., sorbitol
       and glycerin) can lead to diarrhea.

     • Disaccharidase deficiency: It is a lack of enzymes needed to
       break down disaccharides in the gut for absorption (lactase
       deficiency) resulting in an increase in osmotic sugars as lactose
       and sucrose in the intestinal tract.

     • Medications that induce osmotic diarrhea include lactulose and
       magnesium containing antacids and laxatives.

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