Page 144 - COMMUNITY PHARMACY PRACTICE

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Anti-infective agents

• Nifuroxazide (Antinal®)

• Metronidazole (flagyl®) is a nitroimidazole antibiotic for
anaerobic bacteria and protozoa. (POM)

• Antibacterials used for prophylaxis and treatment of
traveler's diarrhea

• Include Azithromycin, fluoroquinolones and rifaximin.

• Sulfonamides, neomycin, doxycycline, tetracycline and TMP-SMX
are no longer recommended due to world-wide drug resistance.

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ANTINAL®

Active constituent : Nifuroxazide

Antinal has a wide bactericidal activity against gram +ve
and gram -ve bacteria: staph , campylobacter , shigella
, salmonella , E. coli , and Yesinia

- it is an intestinal anti-infectious agent

- For acute infectious diarrhea even in pregnancy or in
neonates.(safe, not absorbed)

- It does not destroy the normal intestinal flora and does
not upset the intestinal bacterial equilibrium.

- It has never been found to induce transferable bacterial
resistance

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