Page 142 - COMMUNITY PHARMACY PRACTICE
P. 142

02/04/2024

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Bismuth subsalicylate (BSS)

     • BSS +HCl=B oxychloride insoluble (Poorly absorbed)
       reduce frequency, increase consistency, relieve
       symptoms, decrease cramping, decrease nausea &
       vomiting (salicylate: antisecretory)

     • In traveller s diarrhea (antimicrobial effect of Bi )

     • BSS is indicated as adjuvant to HP (peptic ulcer)

     • Dosage: 2 tablets / 6hrs (max 8/day), liquid

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                                                                                                                          289

Bismuth subsalicylate (BSS)
BSS Not on egyptian market

• Adv effects:

   • toxic salicylate levels (if with aspirin)
   • Tinnitus
   • Black stools, darkening of tongue(harmeless, Bi sulfide)

• Same contraindications of aspirin ( Reys syndrome, gout,
 asthma) overdose of Bi ( neurotoxicity, ..confusion,
 encephalopathy reversible)

• Contra ind (????)

• Drug drug interactions: ( ??

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