Page 141 - COMMUNITY PHARMACY PRACTICE
P. 141
02/04/2024
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IMMODIUM VS LOMOTIL
ü Doesn’t cross BBB ü Cross BBB
thus no CNS sid with CNS side effects
effects or addiction and addiction
ü 2-3 time more ü Less potent than
potent in inhibiting loperamide
diarrhea
ü Sub therapeutic doses of
286 atropine is added to prevent
addiction
287
Adsorbents
• Kaolin is the only monograph adsorbent and it helps to
firm stools within 24 to 48 hours
• Pectin Improve stool consistency (adsorbents, non
selective)
• Contraindications (not children<12yrs)
• Adv effect (no systemic absorption , constipation, bloating rarely)
• Drug drug interation: ……….
• kapect compound POM?
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