Page 73 - phytotherapy_ EBOOK_2025

-There is some concern about the safety of concentrated preparations or
excessive consumption of green tea. Cases of hepatotoxicity have been
associated with consumption of high doses of dietary supplements
containing green-tea (10–29 mg/kg/d p.o.). Hepatotoxicity is mainly
related to the catechin component of green tea.
-In most cases, patients are presented with elevated liver enzymes and
bilirubin levels.
-All cases resolved following cessation of supplement consumption (re-
injury was observed in some studies when the subject began reusing the
same preparations, suggesting a causative effect of the green tea).
(One of the marketed dietary supplements containing green tea extract)
for weight loss was banned in France and Spain in April of 2003 as a
result of 34 cases of green-tea-related toxic liver disease after its
consumption.
Pregnancy and lactation:
Pregnant women should not exceed a dosage of 300 mg per day (5 cups of
tea spread out over the course of a day).
In case of Lactation: Infants whose nursing mothers consume beverages
containing caffeine could suffer from sleep disorders
Drug interactions:
Antiplatelets: “e.g., low dose Aspirin”: Green tea catechins, may have
some antiplatelet effects, which may be additive to those of conventional
antiplatelet drugs. (Potential for increased bleeding, particularly in high
doses of green tea).

72